Modification of the cytoplasmic domain of influenza virus hemagglutinin affects enlargement of the fusion pore

Journal of Virology

Volumn 74, Issue 16, 2000, Pages 7529-7537

  Kozerski, C ^a   Ponimaskin, E ^a   Schroth Diez, B ^a   Schmidt, M F G ^a   Herrmann, A ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCEIN; CELL SURFACE PROTEIN; HEMAGGLUTININ; RHODAMINE B; RNA POLYMERASE;

ANIMAL CELL; ARTICLE; CELL FUSION; CHIMERA; ERYTHROCYTE GHOST; GENE EXPRESSION; HYDROPHOBICITY; INFLUENZA VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MODIFICATION;

ANIMALS; ANTIGENS, CD4; CELL LINE; CELL MEMBRANE; ERYTHROCYTE MEMBRANE; ERYTHROCYTES; FLUORESCEINS; FLUORESCENT DYES; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; INFLUENZA A VIRUS; MEMBRANE FUSION; PROTEIN PRECURSORS; RECOMBINANT FUSION PROTEINS; VACCINIA VIRUS; VIRAL ENVELOPE PROTEINS;

EID: 0033858690     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.16.7529-7537.2000     Document Type: Article

References (39)

1. Extension of the fragment method to calculate amino acid zwitterion and side chain partition coefficients
2. Truncation of the COOH-terminal region of the paramyxovirus SV5 fusion protein leads to hemifusion but not complete fusion
3. Structure of influenza haemagglutinin at neutral and at fusogenic pH by electron cryo-microscopy
4. The dimerization motif of the glycophorin A transmembrane segment in membranes: Importance of glycine residues
5. Structure of influenza hemagglutinin at the pH of membrane fusion
6. 2 to form an N cap that terminates the triple-stranded coiled coil
7. The transmembrane domain in viral fusion: Essential role for a conserved glycine residue in vesicular stomatitis virus G protein
8. Identification of palmitoylation sites on CD4, the human immunodeficiency virus receptor
9. Properties of a viral fusion protein
10. A chimeric avian retrovirus containing the influenza virus gene has an expanded host range
11. +-induced membrane insertion of influenza virus hemagglutinin involves the HA2 amino-terminal fusion peptide but nct the coiled coil region
12. Acylation of the influenza hemagglutinin modulates fusion activity
13. Eucaryotic transient-expression system based on recombinant vaccinia vireos that synthesizes bacteriophage T7 RNA polymerase
14. Fusion activity of the hemagglutinin of influenza virus
15. The influenza virus hemagglutinin cytoplasmic tail is not essential for virus assembly or infectivity
16. GPI- and transmembrane-anchored influenza hemagglutinin differ in structure and receptor binding activity
17. Lipid-anchored influenza hemagglutinin promotes hemifusion, but not complete fusion
18. pH-dependent hydrophobicity profile of hemagglutinin of influenza virus and its possible relevance in virus fusion
19. Structure and topology of the influenza virus fusion peptide in lipid bilayers
20. The lipid-anchored ectodomain of influenza virus hemagglutinin (GPI-HA) is capable of inducing nonenlarging fusion pores
21. GPI-anchored influenza hemagglutinin induces hemifusion to both red blood cell and planar bilayer membranes
22. The role of the cytoplasmic tail region of influenza virus hemaggtutinin in formation and growth of fusion pores
23. Amino acid sequence requirements of the transmembrane and cytoplasmic domains of influenza virus hemagglutinin for viable membrane fusion
24. Meta-stability of the hemifusion intermediate induced by glycosylphosphatidylinositol-anchored influenza hemagglutinin
25. Influence of membrane anchoring and cytoplasmic domains on the fusogenic activity of vesicular stomatitis virus glycoprotein
26. 2 protein
27. Elongation of the cytoplasmic tail interferes with the fusion activity of influenza virus hemagglutinin
28. Assessment of fusogenic properties of influenza virus hemagglutinin deacylated by site-directed mutagenesis and hydroxylamine treatment
29. Domain-structure of cytoplasmic border region is main determinant for palmitoylation of influenza virus hemagglutinin (H7)
30. Specific single or double proline substitutions in the 'spring-loaded' coiled-coil region of the influenza hemagglutinin impair or abolish membrane fusion activity
31. A specific point mutant at position 1 of the influenza hemagglutinin fusion peptide displays a hemifusion phenotype
32. Heterologous transmembrane and cytoplasmic domains direct functional chimeric influenza virus hemagglutinins into the endocytic pathway
33. Molecular cloning: A laboratory manual
34. Fusion activity of transmembrane and cytoplasmic domain chimeras of the influenza virus glycoprotein hemagglutinin
35. Alterations to influenza virus hemagglutinin cytoplasmic tail modulate virus infectivity
36. Coiled coils in both intracellular vesicle and viral membrane fusion
37. Anti-peptide antibodies detect steps in a protein conformational change: Low-pH activation of the influenza virus hemagglutinin
38. The structure and function of the hemagglutinin membrane glycoprotein of influenza virus
39. Structure of the hemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution