Promoter opening by σ54 and σ70 RNA polymerases: σ Factor-directed alterations in the mechanism and tightness of control

Genes and Development

Volumn 14, Issue 17, 2000, Pages 2242-2255

  Guo, Y ^a   Lew, C M ^a   Gralla, J D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

factors; DNA fork junction; NtrC; Promoter opening; Transcription

Indexed keywords

RNA POLYMERASE;

ARTICLE; CROSS LINKING; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE EXPRESSION; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION;

ADENINE; BACTERIAL PROTEINS; BASE SEQUENCE; CROSS-LINKING REAGENTS; DNA; DNA-BINDING PROTEINS; DNA-DIRECTED RNA POLYMERASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HETERODUPLEXES; PII NITROGEN REGULATORY PROTEINS; RNA; RNA POLYMERASE SIGMA 54; SIGMA FACTOR; TEMPERATURE; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0033857305     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.794800     Document Type: Article

References (46)

1. The prokaryotic enhancer binding protein NTRC has an ATPase activity which is phosphorylation and DNA dependent
2. 54) inhibit RNA polymerase isomerization
3. Probing the assembly of transcription initiation complexes through changes in σN protease sensitivity
4. DNA footprints of the two kinetically significant intermediates in formation of an RNA polymerase-promoter open complex: Evidence that interactions with start site and downstream DNA induce sequential conformational changes in polymerase and DNA
5. E. coli promoter opening and -10 recognition: Mutational analysis of σ70
6. Yeast RNA polymerase II at 5 A resolution
7. 54 region I in trans and implications for transcription activation
8. Promoter opening via a DNA fork junction binding activity
9. A fork junction DNA-protein switch that controls promoter melting by the bacterial enhancer-dependent sigma factor
10. Protein-nucleic acid interactions during open complex formation investigated by systematic alteration of the protein and DNA binding partners
11. Protein-protein contacts that activate and repress prokaryotic transcription
12. Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID)
13. 54 transcription activator, PspF, and its DNA-binding mutant, PspFΔHTH
14. Formation of open and elongating transcription complexes by RNA polymerase III
15. High-resolution mapping of nucleoprotein complexes by site-specific protein-DNA photocrosslinking: Organization of the human TBP-TFIIA-TFI-IB-DNA quaternary complex
16. Promoter opening (melting) and transcription initiation by RNA polymerase I requires neither nucleotide β-γ hydrolysis nor protein phosphorylation
17. Calorimetric and spectroscopic investigation of the helix-to-coil transition of the self-complementary deoxyribonucleotide ATGCAT
18. Promoter recognition as measured by binding of polymerase to nontemplate strand oligonucleotide
19. Photoaffinity cross-linking of TaqI restriction endonuclease using an aryl azide linked to the phosphate backbone
20. Mechanism and control of transcription initiation in prokaryotes
21. 54 (sigma N)
22. RNA polymerase unveiled
23. Alterations of highly conserved residues in the regulatory domain of nitrogen regulator I (NtrC) of Escherichia coli
24. Studies of RNA chain initiation by Escherichia coli RNA polymerase bound to T7 DNA. Direct analysis of the kinetics of RNA chain initiation at T7 promoter A2
25. Mutant forms of the enhancer-binding protein NtrC can activate transcription from solution
26. Transcription elongation: Structural basis and mechanisms
27. Structural motifs and potential σ homologies in the large subunit of human general transcription factor TFIIE
28. + but not ATP hydrolysis
29. DNA topology and a minimal set of basal factors for transcription by RNA polymerase II
30. Function of a bacterial activator protein that binds to transcriptional enhancers
31. 70 in promoter-proximal pausing
32. MgATP binding and hydrolysis determinants of NtrC, a bacterial enhancer-binding protein
33. A mutant RNA polymerase that forms unusual open promoter complexes
34. Crucial role of the RNA:DNA hybrid in the processivity of transcription
35. 54
36. Reconstitution of the transcription factor TFIIH: Assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7
37. 54 promoters
38. Polymerase II promoter activation: Closed complex formation and ATP-driven start site opening
39. 54
40. 54 RNA polymerase: Roles for DNA and protein determinants
41. 54 dependent transcription by core promoter sequences: Role of -12 region nucleotides
42. The bacterial enhancer-binding protein NTRC is a molecular machine: ATP hydrolysis is coupled to transcriptional activation
43. The phosphorylated form of the enhancer-binding protein NTRC has an ATPase activity that is essential for activation of transcription
44. RNA polymerase II: Subunit structure and function
45. The use of ATP and initiating nucleotides during postrecruitment steps at the activated adenovirus E4 promoter
46. Crystal structure of Thermus aquaticus core RNA polymerase at 3.3 A resolution