Cytoplasmic cytokines in lymphoproliferative disorders: Multiple cytokine production in angioimmunoblastic lymphadenopathy with dysproteinemia

Leukemia and Lymphoma

Volumn 38, Issue 5-6, 2000, Pages 541-545

  Ohshima, Koichi ^a   Haraoka, Seiji ^a   Suzumiya, Junji ^a   Kawasaki, Chika ^a   Kanda, Motonobu ^a   Kikuchi, Masahiro ^a  

^a FUKUOKA UNIVERSITY   (Japan)

Author keywords

AILD; Angioimmunoblastic lymphadenopathy with dysproteinemia; Cytokines; Cytoplasmic cytokines

Indexed keywords

CD3 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANGIOIMMUNOBLASTIC LYMPHADENOPATHY; ARTICLE; AUTOCRINE EFFECT; B CELL LYMPHOMA; CLINICAL ARTICLE; CYTOKINE PRODUCTION; CYTOPLASM; DYSPROTEINEMIA; HUMAN; HUMAN TISSUE; KIKUCHI DISEASE; LYMPH NODE; LYMPHOPROLIFERATIVE DISEASE; PARACRINE SIGNALING; PATHOGENESIS; PRIORITY JOURNAL; T CELL LEUKEMIA; T CELL LYMPHOMA; T LYMPHOCYTE;

EID: 0033853690     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428190009059273     Document Type: Article

References (16)

1. Hsu, S.M., and Hsu, P.L. (1994) Autocrine and paracrine functions of cytokines in malignant lymphomas. Biomedical Pharmacotherapy, 48, 433-444.
2. Frizzera, G., Moran, E.M., and Rappaport, H. (1974) Angioimmunoblastic lymphadenopathy with dysproteinemia. Lancet, i, 1070-1073.
3. Frizzera, G., Moran, E.M., and Rappaport, H. (1975) Angioimmunoblastic lymphadenopathy. Diagnosis and clinical course. American Journal of Medicine, 59, 803-817.
4. O'Connor, N.T.J., Crick, J.A., Wainscoat, J.S., Gatter, K.C., Stein, H., Falini, B., and Mason, D.Y. (1986) Evidence for monoclonal T lymphocyte proliferation in angioimmunoblastic lymphadenopathy. Journal of Clinical Pathology, 39, 1229-1232.
5. Hsu, S.M., Waldron, J.A., Jr; Fink, L., King, C., Xie, S.S., Mansouri, A., and Barlogie, B. (1993) Pathogenic significance of interleukin-6 in angioimmunoblastic lymphadenopathy-type T-cell lymphoma. Human Pathology, 24, 126-131.
6. Elson, L.H., Nutman, T.B., Metcalfe, D.D., and Prussin, C. (1995) Flow cytometric analysis for cytokine production identifies T helper 1, T helper 2, and T helper 0 cells within the human CD4+ CD27-lymphocyte subpopulution. Journal of Immunology, 154, 4294-4301.
7. Ohshima, K., Kikuchi, M., Masuda, Y., Kobari, S., Sumiyoshi, Y., Eguchi, F., Mohtai, H., Yoshida, T., Takeshita, M., and Kimura, N. (1991) Defective provirus form of human T-cell leukemia virus type I in adult T-cell leukemia/lymphoma: Clinicopathological features. Cancer Research, 51, 4639-4642.
8. Jucker, M., Abts, H., Li, W., Schinndle, R., Merz, H., Gunther, A., von Kalle, C., Schaadt, M., Diamantstein T., Feller, A.C. (1991) Expression of interleukin-6 and interleukin-6 receptor in Hodgkin's disease. Blood, 77, 2413-2418.
9. Uyttenhove, C., Druez, C., Renauld, J.C., Herin, M., Noel, H., Van Snick, J. (1991) Autonomous growth and tumorigenicity induced by p40/interleukin 9 cDNA transfection of a mouse p40-dependent T cell line. Journal of Experimental Medicine, 173, 519-522.
10. Hsu, S.M., Xie, S.S., and Waldron, J.A. Jr. (1992) Functional heterogeneity and pathogenic significance of interleukin-6 in B-cell lymphomas. American Journal of Pathology, 141, 915-923.
11. Macon, W.R., Cousar, J.B., Waldron, J.A. Jr., Hsu, S.M. (1992) Interleukin-4 may contribute to the abundant T-cell reaction and paucity of neoplastic B cells in T-cell rich B cell lymphomas. American Journal of Pathology, 141, 1031-1036.
12. Bertolini, J.N., and Benson, E.M. (1990) The role of human interleukin-6 in B-cell isotype regulation and differentiation of B cells. Cell Immunology, 125, 197-209.
13. Borel, J.F. (1990) Mechanism of action and rationale for cyclosporin a in psoriasis. British Journal of Dermatology, 122, 5-12.
14. Yamamura, M., Honda, M., Yamada, Y., Itoyama, T., Sohda, H., Momita, S., Kamihira, S., Ohmoto, Y., and Tomonaga, M. (1996) Increased levels of interleukin-6 (IL-6) in serum and spontaneous in vitro production of IL-6 by lymph node mononuclear cells of patients with angio-immunoblastic lymphadenopathy with dysproteinemia (AILD), and clinical effectiveness of cyclosporin A. Leukemia, 10, 1504-1508.
15. Paonessa, G., Graziani, R., Serio, A., Savino, R., Ciapponi, L., Lahm, A., Salvati, A.L., Toniatti, C., and Ciliberto, G. (1995) Two distinct and independent sites on IL-6 trigger gp130 dimer formation and signalling. EMBO Journal, 14, 1942-1951.
16. Pizzolo, G., Stein, H., Josimovic-Alasevic, O., Vinante, F., Zanotti, R., Chilosi, M., Feller, A.C., and Diamantstein, T. (1990) Increased serum levels of soluble IL-2 receptor, CD30 and CD8 molecules, and gamma-interferon in angioimmunoblastic lymphadenopathy: possible pathogenetic role of immunoactivation mechanisms. British Journal of Pathology, 75, 485-488.