The prediction of variability occurring in fluidized bed coating equipment. II. The role of nonuniform particle coverage as particles pass through the spray zone

Pharmaceutical Development and Technology

Volumn 5, Issue 3, 2000, Pages 323-332

  Cheng, X X ^a,b   Turton, R ^a  

^a West Virginia University   (United States)

^b Watson Pharmaceuticals Inc   (United States)

Author keywords

Coating uniformity; Fluidized bed; Wurster coating

Indexed keywords

ARTICLE; CHEMICAL ENGINEERING; DRUG COATING; DRUG MANUFACTURE; FLUIDIZED BED; MATHEMATICAL ANALYSIS; PRIORITY JOURNAL;

TECHNOLOGY, PHARMACEUTICAL;

EID: 0033853321     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.1081/PDT-100100547     Document Type: Article

References (6)

1. X. X. Cheng and R. Turton, The prediction of variability occurring in fluidized bed coating equipment. I. The measurement of particle circulation rates in a bottom-spray fluidized bed coater, Pharm. Dev. Technol., 5(3), 311-322 (2000).
2. U. Mann, Coating of Particulate Solids by Air Suspension, Ph.D. Thesis, University of Wisconsin, Madison, WI, 1972.
3. U. Mann, Analysis of spouted-bed coating and granulation. 1. Batch operation, Ind. Eng. Chem. Process Des. Dev., 22, 288-292 (1983).
4. S. Shelukar, J. Ho, J. Zega, E. Roland, N. Yeh, D. Quiram, A. Nole, A. Katdare, and S. Reynolds, Quantification of factors affecting Wurster coating process, Proceedings of the PTF, AIChE Annual Meeting, Miami, Nov. 15-20, 1998, Vol II, pp. 406-411.
5. W. C. Yang, J. Powder Bulk Solids Technol., 62, 89-95 (1977)
6. C. Y. Wen and Y. H. Yu, Mechanics of fluidization, AIChE Symp. Ser., 62, 100-111 (1966).