Inhibition of the vacuolar H+-ATPase perturbs the transport, sorting, processing and release of regulated secretory proteins

European Journal of Biochemistry

Volumn 267, Issue 17, 2000, Pages 5646-5654

  Schoonderwoert, Vincent Th G ^a   Holthuis, Joost C M ^b   Tanaka, Shigeyasu ^c   Tooze, Sharon A ^d   Martens, Gerard J M ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c SHIZUOKA UNIVERSITY   (Japan)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Acidification; Bafilomycin A1; Prohormone processing; Secretory pathway; Vacuolar H+ ATPase

Indexed keywords

BAFILOMYCIN A1; CHROMOGRANIN; FURIN; PROOPIOMELANOCORTIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; SECRETORY PROTEIN;

ANIMAL CELL; ARTICLE; CELL VACUOLE; ENZYME INHIBITION; GOLGI COMPLEX; HYPOPHYSIS INTERMEDIATE LOBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN TARGETING; PROTEIN TRANSPORT; SECRETORY GRANULE; XENOPUS LAEVIS;

ANIMALS; ANTI-BACTERIAL AGENTS; CELL COMPARTMENTATION; ENDOCYTOSIS; GOLGI APPARATUS; HYDROLYSIS; MACROLIDES; PITUITARY GLAND; PROTEIN BIOSYNTHESIS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; PROTON-TRANSLOCATING ATPASES; VACUOLAR PROTON-TRANSLOCATING ATPASES; XENOPUS LAEVIS;

EID: 0033851793     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01648.x     Document Type: Article

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