Cellular and transgenic animal models of cerebrovascular amyloidosis

Molecular Medicine Today

Volumn 6, Issue 9, 2000, Pages 373-374

  Van Nostrand, William E ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID;

AMYLOIDOSIS; ANIMAL MODEL; CEREBROVASCULAR DISEASE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; SHORT SURVEY; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS;

EID: 0033850598     PISSN: 13574310     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-4310(00)01762-7     Document Type: Review

References (5)

1. Verbeek, M.M. et al. (1997) Rapid degeneration of cultured human brain pericytes by amyloid β-protein. J. Neurochem. 68, 1135-1141
2. Van Nostrand, W.E. et al. (1998) Pathogenic cell surface amyloid β-protein fibril assembly in cultured human cerebrovascular smooth muscle cells. J. Neurochem, 70, 216-223
3. Wyss-Coray, T. et al. (1997) Amyloidogenic role of the cytokine TGF-β1 in transgenic mice and in Alzheimer's disease. Nature 389, 603-606
4. Calhoun, M.E. et al. (1999) Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid. Proc. Natl. Acad. Sci. U. S. A. 96, 14088-14093
5. Levy, E. et al. (1990) Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type. Science 248, 1124-1126