The effects of heparin and extracorporeal circulation on platelet counts and platelet microaggregation during cardiopulmonary bypass

Journal of Thoracic and Cardiovascular Surgery

Volumn 120, Issue 3, 2000, Pages 538-543

  Muriithi, Elijah W ^a   Belcher, Philip R ^a   Rao, Jagan N ^a   Chaudhry, Mubarak A ^a   Nicol, Denise ^a   Wheatley, David J ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EDETIC ACID; HEPARIN; HIRUDIN;

ADULT; AGED; ANTICOAGULATION; ARTICLE; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; DRUG MECHANISM; EXTRACORPOREAL CIRCULATION; FEMALE; HEMODILUTION; HEPARINIZATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT;

EID: 0033850594     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1067/mtc.2000.108164     Document Type: Article

References (28)

1. Macroaggregation of platelets in plasma, as distinct from microaggregation in whole blood (and plasma), as determined using optical aggregometry and platelet counting respectively, is specifically impaired following cardiopulmonary bypass in man
2. Blood platelets in cardiopulmonary bypass operations: Recovery occurs after initial stimulation, rather than continual activation
3. Blood platelets and extracorporeal circulation: Kinetic studies on dogs on cardiopulmonary bypass
4. Quantitative detection of platelet aggregates in whole blood without fixation
5. Heparin, platelet aggregation, neutrophils and cardiopulmonary bypass
6. Heparin reversal by protamine in humans-complement, prostaglandins, blood cells, and hemodynamics
7. A new method for the quantitative detection of platelet aggregates in patients with arterial insufficiency
8. Heparin induced platelet dysfunction and cardiopulmonary bypass
9. Heparin effects on plasma lysolecithin formation and platelet aggregation
10. Cardiopulmonary bypass leads to a preferential loss of activated platelets: A flow cytometric assay of platelet surface antigens
11. The platelet function defect of cardiopulmonary bypass
12. Kinetics and sites of sequestration of indium 111-labeled human platelets during cardiopulmonary bypass
13. Fate of indium 111-labeled platelets during cardiopulmonary bypass performed with membrane and bubble oxygenators
14. Influence of cardiopulmonary bypass on platelet and neutrophil accumulations in internal organs
15. Hepatic release of interleukin-10 during cardiopulmonary bypass in steroid-pretreated patients
16. CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells
17. Blood platelets are concentrated near the wall and red blood cells, in the center in flowing blood
18. The flow of model particles and blood cells and its relation to thrombogenesis
19. A double blind study of prostacyclin in cardiopulmonary bypass surgery
20. Prostacyclin in cardiopulmonary bypass operations
21. Integrilin prevents prolonged bleeding times after cardiopulmonary bypass
22. Platelet preservation during cardiopulmonary bypass with iloprost and Duraflo-II heparin-coated surfaces
23. Tirofiban provides 'platelet anesthesia' during cardiopulmonary bypass in baboons
24. Impairment by heparin of primary haemostasis and platelet [14C]5-hydroxytryptamine release
25. Identification of novel heparin-releasable proteins, as well as the cytokines midkine and pleiotrophin, in human postheparin plasma
26. Hirudin as anti-coagulant for cardiopulmonary bypass: Importance of preoperative renal function
27. r-Hirudin inhibits platelet-dependent thrombosis during cardiopulmonary bypass in baboons
28. Argatroban as a potential anticoagulant in cardiopulmonary bypass studies in a dog model