Soluble polymer-supported organic synthesis

Accounts of Chemical Research

Volumn 33, Issue 8, 2000, Pages 546-554

  Toy, P H ^a   Janda, K D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; MACROGOL; ORGANIC COMPOUND; POLYMER; POLYSTYRENE; REAGENT;

ARTICLE; CATALYST; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHEMISTRY; POLYMERIZATION; REACTION ANALYSIS; SOLUBILITY; SYNTHESIS;

INDICATORS AND REAGENTS; ORGANIC CHEMICALS; POLYMERS; SOLUBILITY;

EID: 0033849947     PISSN: 00014842     EISSN: None     Source Type: Journal    
DOI: 10.1021/ar990140h     Document Type: Article

References (49)

1. Solid-phase synthesis
2. Comprehensive Survey of Combinatorial Library Synthesis: 1998
3. Recent developments in solid-phase organic synthesis
4. Organic synthesis on soluble polymer supports: Liquid-phase methodologies
5. Soluble polymers: New options in both traditional and combinatorial synthesis
6. Liquid-phase chemistry: Recent advances in soluble polymer-supported catalysts, reagents and synthesis
7. Parallel synthesis with fluorous reagents and reactants
8. Alternative polymer supports for organic chemistry
9. Liquid-phase synthesis of peptides
10. HELP (High Efficiency Liquid Phase) New oligonucleotide synthesis on soluble polymeric support
11. Oligosaccharide synthesis by the thioglycoside scheme on soluble and insoluble polystyrene supports
12. Polymer-supported solution synthesis of oligosaccharides
13. Polymer-supported solution synthesis of a hepta-glucoside having phytoalexin elicitor activity
14. Polymer-supported solution synthesis of oligosaccharides using a novel versatile linker for the synthesis of D-mannopentaose, a structural unit of D-mannans of pathogenic yeasts
15. Liquid-phase combinatorial synthesis
16. Recursive deconvolution of combinatorial chemical libraries
17. Azatides: Solution and liquid-phase syntheses of a new peptidomimetic
18. A linker that allows efficient formation of aliphatic C-H bonds on polymeric supports
19. Soluble polymer synthesis: An improved traceless linker methodology for aliphatic C-H bond formation
20. Development of new linkers for the formation of aliphatic C-H bonds on polymeric supports
21. Soluble polymer traceless linker investigations: Solvent effects on the desulfonylation of polyethylene glycol (PEG) substituted aryl alkyl sulfones with sodium amalgam
22. Syntheses of alkylated malonates on a traceless linker derived soluble polymer support
23. Expanding on the purification methodology of polyethylene glycol (PEG) bound molecules: The synthesis of 3,5-pyrazolidinediones
24. Solution and soluble polymer syntheses of 3-aminoimidazoline-2-4-diones
25. New perspectives in the cross-coupling reactions of organostannanes
26. Exploring the scope of poly(ethylene glycol) (PEG) as a soluble polymer matrix for the stille cross-coupling reaction
27. Synthesis of peptides in solution on a polymeric support: Synthesis of glycylglycyl-L-leucylglycine
28. Improved solid-phase peptide synthesis on non-crosslinked resins
29. Preparation of soluble polymer supports for peptide synthesis by copolymerization and their utilization for sequential polypeptide synthesis by fragment condensation
30. 2 methyl ester on a soluble-polymer support for the construction of prostanoid libraries
31. 2(α) on a non-crosslinked polystyrene support
32. Straight-forward and General Method for Coupling Alcohols to Solid Supports
33. Soluble-polymer supported synthesis of a prostanoid library: Identification of antiviral activity
34. Immune globulin versus antivirals versus combination for prevention of cytomegalovirus disease in transplant recipients
35. Solution and polymer-supported asymmetric three-component coupling synthesis of six-membered ring prostanoids
36. Solid-supported reagent strategies for rapid purification of combinatorial synthesis products
37. Phase-trafficking reagents and phase-switching strategies for parallel synthesis
38. Solution-phase chemical library synthesis using polymer-assisted purification techniques
39. Soluble polymer-bound ligand-accelerated catalysis: Asymmetric dihydroxylation
40. 2PHAL-PEG-OMe] ligand
41. Multipolymer-supported substrate and ligand approach to the sharpless asymmetric dihydroxylation
42. Poly(ethylene glycol) (PEG) as a reagent support: The preparation and utility of a PEG-triarylphosphine conjugate in liquid-phase organic synthesis (LPOS)
43. Development and application of a poly(ethylene glycol)-supported triarylphosphine reagent: Expanding the sphere of liquid-phase organic synthesis
44. Use of polymers as protecting groups in organic synthesis. IV. Applications of a polystyrylboronic acid resin to the selective functionalization of some glycosides
45. Preparation of a polymer-supported diol and its use in isolating aldehydes and ketones from mixtures and as a protecting group for aldehydes and ketones
46. A soluble polymer approach to the 'fishing out' principle: Synthesis and purification of β-amino alcohols
47. A soluble polymer-supported triflating reagent: A high-throughput synthetic approach to aryl and enol triflates
48. Bifunctional initiators for free-radical polymerization of non-crosslinked block copolymers
49. Soluble supports tailored for organic synthesis via sequential normal/living free radical processes