Synthesis of 1-azabicyclo[3.3.0]octane derivatives and their effects as piracetam-like nootropics

Chemical and Pharmaceutical Bulletin

Volumn 48, Issue 8, 2000, Pages 1121-1124

  Oka, M ^a   Matsumoto, Y ^a   Hirooka, K ^a   Suzuki, T ^a  

^a SANWA KAGAKU KENKYUSHO CO LTD   (Japan)

Author keywords

2 oxo 1 pyrrolidine; 5 nitromethyl 1 azabicyclo 3.3.0 octane; Cerebral function activator; Hydrogenation; Piracetam like nootropics

Indexed keywords

5 AMINOMETHYL 1 AZABICYCLO[3.3.0]OCTANE; 5 NITROMETHYL 1 AZABICYCLO[3.3.0]OCTANE; ANIRACETAM; N [(1 AZABICYCLO[3.3.0]OCTAN 5 YL)METHYL] 2 OXO 1 PYRROLIDINEACETAMIDE; NOOTROPIC AGENT; PIRACETAM; PRAMIRACETAM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN FUNCTION; BRAIN METABOLISM; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGENATION; MOUSE; NONHUMAN; PASSIVE AVOIDANCE; RAT; REACTION ANALYSIS; REPRODUCIBILITY;

EID: 0033848236     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.48.1121     Document Type: Article

References (19)

1. 1H-NMR spectrum of the mixture with that of already-known iminium perchlorate
2. Sodium salts of nitroalkanes appear as intermediates in the Nef Reaction