A case of monoclonal gammopathy associated with acute myelomonocytic leukemia with eosinophilia suggested to be the result of lineage infidelity

American Journal of Hematology

Volumn 65, Issue 1, 2000, Pages 66-71

  Nagata, Toshihito ^a   Mugishima, Hideo ^a   Yoden, Atsushi ^b   Yoshikawa, Kenji ^b   Oguni, Tatsuya ^b   Yamashiro, Kuniaki ^b   Yamamori, Shiyunji ^c   Harada, Kensuke ^a  

^a NIHON UNIVERSITY   (Japan)

^b Hirakata City Hospital   (Japan)

^c Division of Genetic Research Laboratory   (Japan)

Author keywords

Acute myelomonocytic leukemia with eosinophilia; Leukemogenesis; Lineage infidelity; Monoclonal gammopathy

Indexed keywords

IMMUNOGLOBULIN G; IMMUNOGLOBULIN LIGHT CHAIN;

ACUTE MYELOMONOCYTIC LEUKEMIA; ARTICLE; BONE MARROW BIOPSY; CASE REPORT; CELL PROLIFERATION; CYTOGENETICS; DNA DETERMINATION; EOSINOPHILIA; GENE REARRANGEMENT; HUMAN; IMMUNOGLOBULIN GENE; LEUKEMIA CELL; MALE; MONOCLONAL IMMUNOGLOBULINEMIA; MONONUCLEAR CELL; ONCOGENE C MYC; PATHOGENESIS; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PROTO ONCOGENE;

BLOTTING, SOUTHERN; BONE MARROW CELLS; CELL DIVISION; CHILD, PRESCHOOL; DNA; EOSINOPHILIA; GENE REARRANGEMENT; GENES, FOS; GENES, JUN; GENES, MYC; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOPHENOTYPING; LEUKEMIA, MYELOMONOCYTIC, ACUTE; LEUKOCYTES, MONONUCLEAR; MALE; PARAPROTEINEMIAS;

EID: 0033847746     PISSN: 03618609     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-8652(200009)65:1<66::AID-AJH12>3.0.CO;2-T     Document Type: Article

References (25)

1. Multiple myeloma terminating in acute leukemia. Report of 12 cases and review of the literature
2. The chemotherapy of plasma-cell myeloma and the incidence of acute leukemia
3. Multiple myeloma and acute myelomonocytic leukemia
4. Simultaneous presentation of acute myelomonocytic leukemia and multiple myeloma
5. Multiple myeloma and acute myelomonocytic leukemia: Simultaneous occurrence without previous chemotherapy
6. Coexistence of myelomonocytic leukemia and monoclonal gammopathy or myeloma
7. Simultaneous occurrence of myelomonocytic leukemia and multiple myeloma: Involvement of common leukemic progenitors and their developmental abnormality of 'lineage infidelity.'
8. Analysis and cloning of eukaryotic genomic DNA
9. Hemopoietic lineage switch: V-raf oncogene converts Eμ-myc transgenic B cells into macrophages
10. Human acute leukemia cell line with the t(4;11) chromosomal rearrangement exhibits B lineage and monocytic characteristics
11. Clonal relationship of the lymphoblastic cell line P388 to the macrophage cell line P388D1 as evidenced by immunoglobulin gene rearrangements and expression of cell surface antigens
12. Evidence that precursor cells of monocytes and B-lymphocytes are closely related
13. Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells
14. Localization of the human JUN proto-oncogene to chromosome region lp31-32
15. Report of the Committee on Chromosome Changes in Neoplasia
16. MAX: A helix-loop-helix zipper protein that forms a sequence-specific DNA binding complex with Myc
17. Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers
18. Induction of monocytic differentiation and modulation of the expression of c-fos, c-fms, and c-myc protooncogenes in human monoblasts by cytokines and phorbolester
19. The clonal evolution of tumor cell populations. Acquired genetic lability permits stepwise selection of variant sublines and underlies tumor progression
20. Oligoclonal B-cell leukemia characterized by spontaneous cell division and telomere association
21. The cytogenetic scenario of chronic myeloid leukemia
22. Tumor suppressor genes and clonal evolution in B-CLL
23. Common patterns of genetic evolution in human solid tumors
24. A genetic model for colorectal tumorigenesis
25. Evolution of neoplastic cell lineages in Barrett oesophagus