Hyaluronan is not just a goo!

Journal of Clinical Investigation

Volumn 106, Issue 3, 2000, Pages 335-336

  Toole, B P ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; COMPLEMENTARY DNA; GLYCOSAMINOGLYCAN; HERMES ANTIGEN; HYALURONIC ACID; SYNTHETASE;

CELL INTERACTION; CELL MIGRATION; CELL MOTION; EMBRYO DEVELOPMENT; ENDOTHELIUM CELL; EXTRACELLULAR MATRIX; HUMAN; HYDRATION; KNOCKOUT GENE; MALIGNANT TRANSFORMATION; NONHUMAN; NOTE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0033846654     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI10706     Document Type: Note

References (18)

1. Glycosaminoglycans in morphogenesis
2. Structural analyses on the matrical organization of glycosaminoglycans in developing endocardial cushions
3. Effects of hyaluronic acid on cardiac cushion tissue cells in collagen matrix cultures
4. Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediared transformation of epithelium to mesenchyme
5. Hyaluronan synthases
6. Eukaryotic hyaluronan synthases
7. Molecular cloning, identification, and sequence of the hyaluronan synthase gene from group A Streptococcus pyogenes
8. Immuno-chemical confirmation of the primary structure of streptoccocal hyaluronan synthase and synthesis of high molecular weight product by the recombinant enzyme
9. Hyaluronan in morphogenesis and tissue remodeling
10. Hyaluronan
11. Hyaluronic acid binding to CD44 activares Racl and induces lamellipodia outgrowth
12. CD44 interaction with Tiaml promotes Racl signaling and hyaluronic acid-mediated breast tumor cell migration
13. Formation of hyaluronan- and versican-rich pericellular matrix is required for proliferation and migration of vascular smooth muscle cells
14. Localization of matrix metalloproteinase 9 (MMP-9) to the cell surface provides a mechanism for CD44-mediated rumor invasion
15. Overproduction of hyaluronan by expression of the hyaluronan synthase has2 enhances anchorage-independent growth and tumorigenicity
16. Perturbation of hyaluronan interactions by soluble CD44 inhibits growth of murine mammary carcinoma cells in ascites
17. Enhanced transformation by a plasma membrane-associated Met oncoprotein: Activation of a phosphoinositide 3'-kinase-dependent autocrine loop involving hyaluronic add and CD44
18. Ras, protein kinase C, and IkB kinases 1 and 2 are downstream effectors of CD44 during the activation of NF-κB by hyaluronic acid fragments in T-24 carcinoma cells