T-lymphocyte subpopulations do not express identical combinations of interleukin-2 receptor chains in the early phase of their activation and proliferation

Scandinavian Journal of Immunology

Volumn 52, Issue 2, 2000, Pages 123-130

  Perola, ^a,b   Ripatti, ^a,b   Pelkonen, ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 2 RECEPTOR; OKT 3; RECEPTOR SUBTYPE;

ARTICLE; CELL ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE SUBPOPULATION;

ANTIGENS, CD45; BIOLOGICAL MARKERS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIVISION; HUMANS; IMMUNOLOGIC MEMORY; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; PHENOTYPE; RECEPTORS, INTERLEUKIN-2; T-LYMPHOCYTE SUBSETS;

EID: 0033846345     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.2000.00751.x     Document Type: Article

References (32)

1. CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development
2. Differential expression and regulation of cytokine mRNAs in normal human CD45R T cell subsets
3. Naive and memory T cells show distinct pathways of lymphocyte recirculation
4. Distinction of naive and memory BoCD4 lymphocytes in calves with a monoclonal antibody, CC76, to a restricted determinant of the bovine leukocyte-common antigen, CD45
5. Human naive and memory T cells: Reinterpretation of helper-inducer and suppressor-inducer subsets
6. T-cell memory: The connection between function, phenotype and migration pathways
7. Is T-cell memory maintained by crossreactive stimulation?
8. Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production
9. Control of lymphocyte recirculation in man. I. Differential regulation of the peripheral lymph node homing receptor L-selection on T cells during the virgin to memory cell transition
10. Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells
11. Heterogeneity of the human CD4+ T-cell population: Two distinct CD4+ T-cell subsets characterized by coexpression of CD45RA and CD45RO isoforms
12. CD4+ T-cell memory, CD45R subsets and the persistence of antigen - A unifying concept
13. Lifespan of human lymphocyte subsets defined by CD45 isoforms
14. Cyclic regulation of CD45 isoform expression in a long term human CD4+CD45RA+ T cell line
15. Loss of activation-induced CD45RO with maintenance of CD45RA expression during prolonged culture of T cells and NK cells
16. Rapid re-expression of CD45RC on rat CD4 T cells in vitro correlates with a change in function
17. Identical expression of CD45R isoforms by CD45RC+ 'revertant' memory and CD45RC+ naive CD4 T cells
18. CD45RC isoforms define two types of CD4 memory T cells, one of which depends on persisting antigen
19. Interconversion of CD45R subsets of CD4 T cells in vivo
20. The IL-2 receptor complex: Its structure, function, and target genes
21. The common gamma-chain for multiple cytokine receptors
22. Expression of the IL-2 receptor gamma chain on various populations in human peripheral blood
23. A novel subpopulation of CD45RA+ CD4+ T cells expressing IL-2 receptor alpha-chain (CD25) and having a functionally transitional nature into memory cells
24. Preferential expression of IL-2 receptor subunits on memory populations within CD4+ and CD8+ T cells
25. Expression of the IL-2 receptor gamma subunit in resting human CD4 T lymphocytes: mRNA is constitutively transcribed and the protein stored as an intracellular component
26. Differential expression of the IL-2 receptor subunits, p55 and p75 on various populations of primary peripheral blood mononuclear cells
27. Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies
28. Activation of naive and memory T cells by interleukin-15
29. The expression of interleukin-2 receptor subunits on the different human periferal blood mononuclear cell subsets displays a highly sensitive profile
30. Interleukin-2 receptor beta chain gene: Generation of three receptor forms by cloned human alpha and beta chain cDNA's
31. Hyporesponsiveness of 'naive' (CD45RA+) human T cells to multiple receptor-mediated stimuli but augmentation of responses by co-stimuli
32. The duration of antigenic stimulation determines the fate of naive and effector T cells