Inhibitory effects of malotilate on in vitro invasion of lung endothelial cell monolayer by human oral squamous cell carcinoma cells

Tumor Biology

Volumn 21, Issue 5, 2000, Pages 299-308

  Shibata, Toshiyuki ^a   Nagayasu, Hiroki ^a   Hamada, Jun Ichi ^b   Konaka, Shigeo ^c   Hosokawa, Masuo ^b   Kawano, Takashi ^a   Kitajo, Hiroyuki ^a   Arisue, Makoto ^a  

^a HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c NIHON NOHYAKU CO LTD   (Japan)

Author keywords

Endothelial cell; Gap junction; Invasion; Malotilate; Oral cancer; Squamous cell carcinoma

Indexed keywords

CONNEXIN 43; DESMOGLEIN; MALOTILATE; MATRIGEL; OCCLUDIN;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INVASION; CELL CULTURE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; GAP JUNCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG ENDOTHELIUM; MOUTH CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; TIGHT JUNCTION;

EID: 0033844403     PISSN: 10104283     EISSN: None     Source Type: Journal    
DOI: 10.1159/000030135     Document Type: Article

References (31)

1. Heiss MM, Allgayer H, Gruetzner KU, et al: Individual development and uPA-receptor expression of disseminated tumour cells in bone marrow: A reference to early systemic disease in solid cancer. Nat Med 1995;1:1035-1039.
2. Osborn MP, Rosen PP: Detection and management of bone marrow micrometastasis in breast cancer. Oncology 1994;8:25-31.
3. Lindeman F, Schlimok G, Dirschedl P. et al: Prognostic significance of micrometastatic tumor cells in bone marrow of colorectal cancer patients. Lancet 1992;340:685-689.
4. Poste G, Filder IJ: The pathogenesis of cancer metastasis. Nature 1980;283:139-146.
5. Liotta LA: Tumor invasion and metastasis - Role of the extracellular matrix. Cancer Res 1986;46:1-7.
6. Nicolson GL: Cancer metastasis: Tumor cell and host organ properties important in metastasis to specific secondary sites. Biochim Biophys Acta 1988;948:175-224.
7. Nicolson GL: Metastatic tumor cell interactions with endothelium, basement membrane and tissue. Curr Opin Cell Biol 1989;1:1009-1019.
8. Pauli BU, Augustin-Voss HG, El-Sabban ME, et al: Organ preference of metastasis. The role of endothelial cell adhesion molecules. Cancer Metastasis Rev 1990;9:175-189.
9. Kato M, Sugimoto T: Effect of malotilate on chronic liver injury induced by carbon tetrachloride in rats. Folia Pharmacol Jpn 1982;80:83-91.
10. Nokata M, Katho M, Tanaka T, et al: Protective effect of malotilate (diisopropyl-1, 3-dithiol-2-ylidenemalonate) on carbon tetrachloride-induced liver injury in mice and rats. J Toxicol Sci 1985;10:279-288.
11. Ryle PR, Dumont JM: Malotilate: The new hope for a clinically effective agent for the treatment of liver disease. Alcohol Alcohol 1987;22:121-141.
12. Imaizumi Y, Katoh M, Sugimoto T: Effect of malotilate (diisopropyl-1, 3-dithiol-2-ylidenemalonate) on the synthesis and movement of RNA in rat liver. Folia Pharmacol Jpn 1982;79:285-291.
13. Imaizumi Y, Katoh M, Sugimoto T, et al: Effect of malotilate (diisopropyl-1, 3-dithiol-2-ylidenemalonate) on the protein synthesis of the rat liver. Jpn J Pharmacol 1982;32:369-375.
14. Wakasugi J, Tomikawa J: Stimulatory effect of malotilate on protein synthesis in hepatocytes: in New Trends in Peptic Ulcer and Chronic Hepatitis. 2. Chronic Hepatitis. Tokyo, Excerpta Medica. 1987, pp 342-346.
15. Zijlstra FJ, Wilson JHP, Vemeer MA, et al: Differential effects of malotilate on 5-, 12-and 15-lipoxygenase in human ascites cells. Eur J Pharmacol 1989;159:291-295.
16. Sunada H, Masuda M, Fujiwara K: Preservation of differentiated phenotypes in cultured aortic endothelial cells by malotilate and phosphoascorbic acid. Eur J Cell Biol 1993;60:48-56.
17. Nagayasu H, Hamada J-i, Kawano T, et al: Inhibitory effects of malotilate on invasion and metastasis of rat mammary carcinoma cells by modifying the functions of vascular endothelial cells. Br J Cancer 1998;77:1371-1377.
18. Nakajima M, Lotan D, Baig MM, et al: Inhibition by retinoic acid of type IV collagenolysis and invasion through reconstituted basement membrane by metastatic rat mammary adenocarcinoma cells. Cancer Res 1989;49:1698-1706.
19. Ohigashi H, Shinkai K, Mukai M, et al: In vitro invasion of endothelial cell monolayer by rat ascites hepatoma cells. Jpn J Cancer Res 1989;80:818-821.
20. Albini A, Iwamoto H, Kleinman HK, et al: A rapid in vitro assay for quantitating the invasive potential of tumour cells. Cancer Res 1987;47:3239-3245.
21. Humphries MJ, Olden K, Yamada KM: A synthetic peptide from fibronectin inhibits experimental metastatsis of murine melanoma cells. Science 1986;233:467-470.
22. Iwamoto Y, Robey FA, Graf J, et al: YIGSR. a synthetic laminin pentapeptide, inhibits experimental metastasis formation. Science 1987;238:1132-1134.
23. Saiki I, Iida J, Murata J, et al: Inhibition of the metastasis of murine malignant melanoma by synthetic polymeric peptides containing core sequence of cell-adhesive molecules. Cancer Res 1989;49:3815-3822.
24. Fujita S, Suzuki H, Kinoshita M, et al: Inhibition of cell attachment, invasion and metastasis of human carcinoma cells by anti-integrin β1 subunit antibody. Jpn J Cancer Res 1992;83:1317-1326.
25. Kawaguchi S, Kikuchi K, Ishii S, et al: VLA-4 molecules on tumor cells initiate an adhesive interaction with VCAM-1 molecules on endothelial cell surface. Jpn J Cancer Res 1992;83:1304-1316.
26. Schultz RM, Silbeman S, Persky B, et al: Inhibition by human recombinant tissue inhibitor of metalloproteinases of human amnion invasion and lung colonization by murine B16-F10 melanoma cells. Cancer Res 1988;48:5539-5545.
27. Cajot JF, Bamat J, Bergonzelli GE, et al: Plasminogen-activator inhibitor type I is a potent natural inhibitor of extracellular matrix degradation by fibrosarcoma and colon carcinoma cell. Proc Natl Acad Sci USA 1990;87:6939-6943.
28. Albini A, Melchiori A, Santi L, et al: Tumor cell invasion inhibited by TIMP-2. J Natl Cancer Inst 1991;83:775-779.
29. Khokha R, Zimmer MJ, Graham CH. et al: Suppression of invasion by inducible expression of tissue inhibitor of metalloproteinase-1 (TIMP-1) in B16-F10 melanoma cells. J Natl Cancer Inst 1992;84:1017-1022.
30. Ingbeer D, Fujita T, Kishimoto S, et al: Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumor growth. Nature 1990;348:555-557.
31. O'Reilly MS, Holmgren L, Shing Y, et al: Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 1994;79:315-328.