Improvement of intestinal absorption of peptides: Adsorption of B1-Phe monoglucosylated insulin to rat intestinal brush-border membrane vesicles

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 50, Issue 2, 2000, Pages 197-204

  Hashimoto, Tadashi ^a,b   Nomoto, Masahiro ^a,c   Komatsu, Kazuki ^a   Haga, Makoto ^a   Hayashi, Masahiro ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

^c MEIJI SEIKA KAISHA LTD   (Japan)

Author keywords

Brush border membrane vesicles; Glycosylation; Hypoglycemic effect; Insulin; Na+ dependent D glucose transporter

Indexed keywords

INSULIN DERIVATIVE; INSULIN[4 (SUCCINYLAMIDO) PHENYL ALPHA DEXTRO GLUCOPYRANOSIDE]; INSULIN[B1 PHENYLALANINE]; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRUSH BORDER; CONTROLLED STUDY; DRUG ABSORPTION; DRUG ADSORPTION; GLYCOSYLATION; HYPOGLYCEMIA; IMMUNOREACTIVITY; INTESTINE ABSORPTION; MEMBRANE PERMEABILITY; MEMBRANE VESICLE; NONHUMAN; OSMOLARITY; RAT;

ADSORPTION; ANIMALS; BLOOD GLUCOSE; GLYCOSYLATION; INSULIN; INTESTINAL ABSORPTION; INTESTINE, SMALL; MALE; MICROVILLI; MONOSACCHARIDE TRANSPORT PROTEINS; RATS; RATS, WISTAR;

EID: 0033844240     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(00)00082-5     Document Type: Article

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