K+ channel inhibition, calcium signaling, and vasomotor tone in canine pulmonary artery smooth muscle

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 279, Issue 2 23-2, 2000, Pages

  Doi, Shouzaburoh ^a   Damron, Derek S ^a   Ogawa, Koji ^a   Tanaka, Satoru ^a   Horibe, Mayumi ^a   Murray, Paul A ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Intracellular calcium; Pulmonary circulation; Vasoconstriction; Voltage gated potassium channels; adrenoreceptor activation

Indexed keywords

4 AMINOPYRIDINE; ALPHA ADRENERGIC RECEPTOR; CALCIUM CHANNEL; CALCIUM ION; CHARYBDOTOXIN; GLIBENCLAMIDE; LEMAKALIM; METHIONINE ADENOSYLTRANSFERASE; POTASSIUM CHANNEL; POTASSIUM ION;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CONDUCTANCE; CALCIUM SIGNALING; CONTROLLED STUDY; DOG; DOSE RESPONSE; LUNG CIRCULATION; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; SARCOPLASMIC RETICULUM; SMOOTH MUSCLE; VASOCONSTRICTION; VASOMOTOR REFLEX;

EID: 0033844189     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2000.279.2.l242     Document Type: Article

References (43)

1. + channels in pulmonary arterial smooth muscle cells isolated from the rat
2. 2+ signaling in rat arterial smooth muscle cells under the control of local renin-angiotensin system
3. + current in rat saphenous artery
4. Inositol trisphosphate and calcium signaling
5. Regulation of arterial tone by activation of calcium-dependent potassium channels
6. 1(B)-adrenoreceptor-mediated contraction to phenylephrine of the rat spleen
7. Culture techniques and their applications to studies of vascular smooth muscle
8. + channels regulate resting potential of pulmonary arterial smooth muscle cells
9. 2+ stores and activates an influx pathway for divalent cations in HL-60 cells
10. 2+ entry and tyrosine kinase activation in canine pulmonary arterial smooth muscle cells
11. 2+ influx: How many mechanisms for how many channels?
12. Mechanisms for the positive inotropic effect of alpha 1-adrenoreceptor stimulation in rat cardiac myocytes
13. 2+ transients in isolated guinea pig coronary myocytes
14. + channels
15. 2+ indicators with greatly improved fluorescence properties
16. 2+-oscillations in vascular myocytes from the rat pulmonary artery
17. 2+ dependence and physiological implication
18. 2+ concentration in rat pulmonary artery myocytes
19. 2+ oscillations in canine pulmonary artery smooth muscle cells
20. + channel blockers on vascular tone in the perfused rat lung
21. Cellular mechanisms and role of endothelin-1-induced calcium oscillations in pulmonary arterial myocytes
22. Membrane hyperpolarization inhibits agonist-induced synthesis of inositol 1,4,5-trisphosphate in rabbit mesenteric artery
23. Protein kinase C-dependent and -independent increases in myofilament calcium sensitivity in response to α-adrenoreceptor activation in pulmonary artery smooth muscle
24. 1-Adrenergic receptor subtypes
25. + channels and depolarizes smooth muscle cells of porcine coronary artery
26. + channels is involved in arterial dilations to calcitonin gene-related peptide
27. Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone
28. Physiological roles and properties of potassium channels in arterial smooth muscle
29. Effect of pretreating rat atria with potassium channel blocking drugs on the electrical and mechanical responses to phenylephrine
30. Features of 4-aminopyridine sensitive outward current observed in single smooth muscle cells from the rabbit pulmonary artery
31. Direct role for potassium channel inhibition in hypoxic pulmonary vasocon-striction
32. + channels and their modulation by endothelin-1 in rat pulmonary arterial smooth muscle cells
33. ATP-sensitive potassium channel is essential to maintain basal coronary vascular tone in vivo
34. 2+-influx pathway
35. 2 agonist, inhibits K(Ca) channel activity from pig coronary artery
36. + channel agonist, lemakalim
37. Two distinct membrane currents activated by cyclopiazonic acid-induced calcium store depletion in single smooth muscle cells of the mouse anococcygeus
38. + channels modulate vasoconstrictor responses to severe hypoxia in isolated ferret lungs
39. 2+](i) in pulmonary arterial myocytes
40. + channels in pulmonary artery smooth muscle cells of patients with primary pulmonary hypertension
41. Nitric oxide inhibits serotonin-induced calcium release in pulmonary artery smooth muscle cells
42. Hypoxia reduces potassium current in cultured rat pulmonary but not mesenteric arterial myocytes
43. 2+ conductances in pulmonary artery cells