Constitutional mosaic trisomies, mutations, and deletions in cancer: A hypothesis [3]

Cancer Genetics and Cytogenetics

Volumn 121, Issue 1, 2000, Pages 103-105

  Mark, H F L ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER; CANCER SUSCEPTIBILITY; GENE EXPRESSION; HUMAN; LETTER; MEIOSIS; MOSAICISM; NONDISJUNCTION; PRIORITY JOURNAL; RECESSIVE GENE; SOMATIC CELL GENETICS; TRISOMY;

CHROMOSOME DELETION; HUMANS; MALE; MEIOSIS; MUTATION; NEOPLASMS; TRISOMY;

EID: 0033844026     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(00)00220-X     Document Type: Letter

References (8)

1. Ahmed M.N., Kim K., Haddad B., Berchuck A., Qumsiyeh M.B. Comparative genomic hybridization studies in hydatidiform moles and choriocarcinoma. amplification of 7q21-q31 and loss of 8p12-p21 in choriocarcinoma Cancer Genet Cytogenet. 116:2000;10-15.
2. Bova G.S., MacGrogan D., Levy A., Pin S.S., Bookstein R., Isaac W.B. Physical mapping of chromosome 8p22 markers and their homozygous deletion in a metastatic prostate cancer. Genomics. 35:1996;46-54.
3. MacGrogan D., Levy A., Bova G.S., Isaac W.B., Bookstein R. Structure and methylation-associated silence of a gene within a homozygously deleted region of human chromosome band 8p22. Genomics. 35:1996;55-56.
4. Mark H.F.L., Ahearn J., Lathrop J. Constitutional trisomy 8 mosaicism and gestational trophoblastic disease. Cancer Genet Cytogenet. 80:1995;150-154.
5. Mark H.F.L., Afify A., Taylor W., Santoro K., Lathrop J.C. A subset of gestational trophoblastic disease characterized by abnormal chromosome 8 copy number detected by fluorescent in situ hybridization. Cancer Genet Cytogenet. 99:1997;24-29.
6. Mark H.F.L. Phenotypic variability in trisomy 8 mosaicism is consistent with the hypothesis of meiotic origin of trisomic neoplasms. Cancer Genet Cytogenet. 76:1994;158.
7. Mark H.F.L. Constitutional trisomy 8 mosaicism and cancer. Cancer Genet Cytogenet. 81:1995;1-2.
8. Seghezzi L., Maserati E., Minelli A., Dellavecchia C., Addis P., Locatelli F., Angioni A., Balloni P., Miano C., Cavalli P., Danesino C., Pasquali F. Constitutional trisomy 8 as first mutation in multistep carcinogenesis. clinical, cytogenetic, and molecular data on three cases Genes Chromosom Cancer. 17:1996;94-101.