Low density lipoproteins in human plasma make vascular smooth muscle cells resistant to growth inhibition by heparin

Cardiovascular Research

Volumn 47, Issue 4, 2000, Pages 749-758

  Underwood, P A ^a   Mitchell, Sue M ^a  

^a CSIRO   (Australia)

Author keywords

Atherosclerosis; Cell culture isolation; Growth factors; Lipoproteins; Restenosis; Smooth muscle

Indexed keywords

HEPARIN; LOW DENSITY LIPOPROTEIN;

ARTICLE; CELL HYPERPLASIA; CONTROLLED STUDY; GROWTH INHIBITION; HUMAN; HUMAN CELL; LIPOPROTEIN METABOLISM; PLASMA; PRIORITY JOURNAL; RESTENOSIS; VASCULAR SMOOTH MUSCLE;

ADULT; ANIMALS; CATTLE; CELL DIVISION; CELLS, CULTURED; CORONARY DISEASE; CULTURE MEDIA, CONDITIONED; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEPARIN; HUMANS; LIPOPROTEINS, LDL; MUSCLE, SMOOTH, VASCULAR;

EID: 0033843792     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(00)00129-2     Document Type: Article

References (38)

1. Underwood P.A., Mitchell S.M., Whitelock J.M. Heparin fails to inhibit the proliferation of human vascular smooth muscle cells in the presence of human serum. J. Vasc. Res. 35:1998;449-460.
2. Faxon D.P., Spiro T.E., Minor S., et al. Low molecular weight heparin in prevention of restenosis after angioplasty - results of enoxaparin restenosis (ERA) trial. Circulation. 90:1994;908-914.
3. Brack M.J., Ray S., Chauhan A., et al. The subcutaneous heparin and angioplasty restenosis prevention (SHARP) trial: results of a multicenter randomized trial investigating the effects of high dose unfractionated heparin on angiographic restenosis and clinical outcome. J. Am. Coll. Cardiol. 26:1995;947-954.
4. Cairns J.A., Gill J., Morton B., et al. Fish oils and low-molecular-weight heparin for the reduction of restenosis after percutaneous transluminal coronary angioplasty - the EMPAR study. Circulation. 94:1996;1553-1560.
5. McKay E.J., Laurell C.B. The interaction of heparin with plasma proteins. Demonstration of different binding sites for antithrombin III complexes and antithrombin III. J. Lab. Clin. Med. 95:1980;69-80.
6. Zammit A., Pepper D.S., Dawes J. Interaction of immobilised unfractionated and LMW heparins with proteins in whole human plasma. Thrombosis and Haemostasis. 70:1993;951-958.
7. Brown A.J., Dean R.T., Jessup W. Free and esterified oxysterol formation during Cu++ oxidation of LDLs and uptake by macrophages. J. Lipid Res. 37:1996;320-335.
8. Resink T.J., Bochkov V.N., Hahn A.W., Philippova M.P., Buhler F.R., Tkachuk V.A. Low- and high- density lipoproteins as mitogenic factors for vascular smooth muscle cells: individual, additive and synergistic effects. J. Vasc. Res. 32:1995;328-338.
9. Underwood P.A., Bean P.A., Whitelock J.M. Inhibition of endothelial cell adhesion and proliferation by extracellular matrix from vascular smooth muscle cells: role of type V collagen. Atherosclerosis. 141:1998;141-152.
10. Neylon C.B., Little P.J., Cragoe Jr E.J., Bobik A. Intracellular pH in human arterial smooth muscle. Circ. Res. 67:1990;814-825.
11. Underwood P.A., Bean P.A. Extracellular matrix interferes with colorimetric estimation of cell number. In Vitro Cell. Dev. Biol.- Animal. 34:1998;200-202.
12. Colquhoun D. Lectures on biostatistics. 1971;Clarendon Press, Oxford.
13. Castellot J.J., Wong K., Herman B., et al. Binding and internalisation of heparin by vascular smooth muscle cells. J. Cell. Physiol. 124:1985;13-20.
14. Lemire J.M., Covin C.W., White S., Giachelli C.M., Schwartz S.M. Characterisation of cloned aortic smooth muscle cells from young rats. J. Pathol. 144:1994;1068-1081.
15. Conrad H.E. Heparin binding proteins. 1998;Academic Press.
16. Libby P., Miao P., Ordovas J.M., Schaefer E.J. Lipoproteins increase growth of mitogen-stimulated arterial smooth muscle cells. J. Cell Physiol. 124:1985;1-8.
17. Tenda K., Saikawa T., Maeda T., et al. The relationship between serum lipoprotein (a) and restenosis after initial elective percutaneous transluminal coronary angioplasty. Jap. J. Circulation. 57:1993;789-795.
18. Maca T., Ahmadi R., Derfler K., et al. Elevated lipoprotein (a) and increased incidence of restenosis after femoropopliteal PTA Rationale for the higher risk of recurrence in females. Atherosclerosis. 127:1996;27-34.
19. Horie H., Takahashi M., Izumi M., et al. Association of an acute reduction in lipoprotein (a) with coronary artery restenosis after percutaneous transluminal coronary angioplasty. Circulation. 96:1997;166-173.
20. Miyata M., Biro S., Kaieda H., Tanaka H. Lipoprotein (a) stimulates the proliferation of cultured human arterial smooth muscle cells through two pathways. FEBS Letts. 377:1995;493-496.
21. Tkachuk V.A., Kuzmenko Y.S., Resink T.J., Stambolsky T.V., Bochkov V.N. Atypical low density lipoprotein binding site that may mediate lipoprotein-induced signal transduction. Mol. Pharmacol. 46:1994;1129-1137.
22. Bochkov V.N., Tkachuk V.A., Philippova M.P., Stambolsky D.V., Buhler F.R., Resink T.J. Ligand selectivity of 105 kDa and 130 kDa lipoprotein-binding proteins in vascular smooth muscle cell membranes is unique. Biochem. J. 317:1996;297-304.
23. Stiko-Rham A., Hultgardh-Nilsson A., Regnstrom J., Hamsten A., Nilsson J. Native and oxidised LDL enhances production of PDGF AA and the surface expression of PDGF receptors in cultured human smooth muscle cells. Arterioscler. Thromb. 12:1992;1099-1109.
24. Polanco J.I., Albajar M., Pocovi M., Rodriguez-Rey J.C. Induction of insulin-like growth factor receptor (IGF IR) mRNA levels by low density lipoproteins. Biochem. Biophys. Res. Comm. 226:1996;917-922.
25. Zwijsen R.M., Japenga S.C., Heijen A.M., van der Bos R.C., Koeman J.H. Induction of platelet-derived growth factor chain A gene expression in human smooth muscle cells by oxidised low density lipoproteins. Biochem. Biophys. Res. Comm. 186:1992;1410-1416.
26. Chai Y.-C., Howe P.H., DiCorleto P.E., Chisolm G.M. Oxidised low density lipoprotein and lysophosphatidylcholine stimulate cell cycle entry in vascular smooth muscle cells. J. Biol. Chem. 271:1996;17791-17797.
27. Ananyeva N.M., Tjurmin A.V., Berliner J.A., et al. Oxidised LDL mediates the release of fibroblast growth factor-1. Arterioscler. Thromb. Vasc. Biol. 17:1997;445-453.
28. Bjorkerud S., Bjorkerud B. Growth-stimulating effect of lipoproteins on human arterial smooth-muscle cells and lung fibroblasts is due to Apo-B-containing lipoproteins, type LDL and VLDL, and requires LDL receptors. Biochim. Biophys. Acta. 1268:1995;237-247.
29. Scott-Burden T., Resink T.J., Hahn A.W.A., Baur U., Box R.J., Buhler F.R. Induction of growth-related metabolism in human vascular smooth muscle cells by low density lipoprotein. J. Biol. Chem. 264:1989;12582-12589.
30. Chen J.K., Hoshi H., McKeehan W.L. Heparin-binding growth factor type one and platelet-derived growth factor are required for the optimal expression of cell surface low density lipoprotein receptor binding activity in human adult arterial smooth muscle cells. In Vitro Cell Dev. Biol. 24:1988;199-204.
31. Ikeda U., Oguchi A., Okada K., et al. Involvement of LDL receptor in the proliferation of vascular smooth muscle cells. Atherosclerosis. 110:1994;87-94.
32. Yamaguchi H., Lee Y.J., Daida H., et al. Effectiveness of LDL-apheresis in preventing restenosis after percutaneous transluminal coronary angioplasty (PTCA): LDL Apheresis Angioplasty Restenosis Trial (L-ART). Chem. Phys. Lipids. 67-68:1994;399-403.
33. Adachi H., Niwa A., Shinoda T. Prevention of restenosis after coronary angioplasty with low-density lipoprotein apheresis. Artificial Organs. 19:1995;1243-1247.
34. Lorenzini J.L., Dutrillaux F., Mousson C., Lassale B., Maynadie M., Rifle G. Extracorporeal circuit heparinisation in selective low density lipoprotein apheresis: changes in patient hemostasis and low molecular weight heparin benefit. J. Clin. Apheresis. 8:1993;141-146.
35. Tamai O., Matsuoka H., Itabe H., Wada Y., Kohno K., Imaizumi T. Single LDL apheresis improves endothelium-dependent vasodilation in hypercholesterolemic humans. Circulation. 95:1997;76-82.
36. Chan P., Patel M., Betteridge L., et al. Abnormal growth regulation of vascular smooth muscle cells by heparin in patients with restenosis. Lancet. 341:1993;341-342.
37. Refson J.S., Schachter M., Patel M.K., et al. Vein graft stenosis and the heparin responsiveness of human vascular smooth muscle cells. Circulation. 97:1998;2506-2510.
38. San Antonio J.D., Verrecchio A., Pukac L.A. Heparin sensitive and resistant vascular smooth muscle cells: biology and role in restenosis. Connect Tissue Res. 37:1998;87-103.