Diminished chemokine and cytokine-induced adhesion of CD4+T cells to extracellular matrix ligands in patients with end-stage renal failure

Israel Medical Association Journal

Volumn 2, Issue 4, 2000, Pages 282-286

  Zeltzer, E ^a   Bernheim, J ^a   Korzets, Z ^a   Zeeli, D ^a   Rathaus, M ^a   Mekori, Y A ^a   Hershkoviz, R ^a  

^a MEIR MEDICAL CENTER   (Israel)

Author keywords

CD4+T cell; Cell adhesion molecules; Chemokines; Cytokines; Dialysis; Extracellular matrix; Integrins; Tumor necrosis factor ; Uremia

Indexed keywords

CD4 ANTIGEN; CHEMOKINE; CYTOKINE; LIGAND; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; RANTES; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL ADHESION; CELLULAR IMMUNITY; CONTROLLED STUDY; DIALYSIS; DOSE RESPONSE; EXTRACELLULAR MATRIX; HUMAN; IMMUNE RESPONSE; KIDNEY FAILURE; MAJOR CLINICAL STUDY; T LYMPHOCYTE; UREMIA;

CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CELL ADHESION; CHEMOKINES; CYTOKINES; EXTRACELLULAR MATRIX; HUMANS; IMMUNITY, CELLULAR; INTEGRINS; KIDNEY FAILURE, CHRONIC; MACROPHAGE INFLAMMATORY PROTEIN-1; RANTES; RENAL DIALYSIS; TUMOR NECROSIS FACTOR-ALPHA; UREMIA;

EID: 0033843154     PISSN: 15651088     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Immunological considerations of the uraemic and dialysed patient
2. Immune dysfunction in uraemia
3. Mortality in dialysis patients: Analysis of the causes of death
4. T cell subsets and cellular immunity in end-stage renal disease
5. Immune deficiency of the uraemic patient
6. Defective cellular immunity in renal failure: Depression of reactivity of lymphocytes to phytohemagglutinin by renal failure serum
7. Immunosuppressive factors in uraemic sera composed of both dialysable and non-dialysable components
8. Humoral inhibitors of the immune response in uraemia. II: The immunosuppressive factor of uremic rat serum is a very low density lipoprotein
9. Adhesion receptors of the immune system
10. 1-integrin (CD29) receptors: Mediators of T lymphocyte extracellular matrix recognition that affect adhesion, activation and lyphokine secretion
11. Adhesion molecules. Part I
12. Interactions of migrating lymphocytes, inflammatory mediators, and the extra cellular matric
13. TNF-α associated with fibronectin enhances phorbol myristate acetate- or antigen mediated integrin-dependent adhesion of CD4+T cells via protein tyrosine phosphorylation
14. Chemokines: Leukocyte recruitment and activation cytokines
15. Chemokines - Chemotactic cytokines that mediate inflammation
16. Regulation of adhesion of CD4+T lymphocytes to intact or heparinase-treated subendothelial extracellular matrix by diffusible or anchored RANTES and MIP-1β
17. Inhibition by uraemic sera of CD4+T cell adhesion to extracellular matrix components
18. Diminished adhesion of CD4+T cells from dialysis patients to extracellular matrix and its components fibronectin and laminin
19. Thrombin adhesive properties: Induction by plasmin and heparan sulfate
20. Structure and function of leucocyte integrins
21. Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines
22. Chemokines and T lymphocyte activation. I: Chemokines costimulate human T lymphocyte activation in vitro
23. Balance between IL-1 beta, TNF-alpha, and their inhibitors in chronic renal failure and maintenance dialysis. Relationships with activation markers of T cells, B cells, and monocytes
24. Soluble tumor necrosis factor receptors are increased in hemodialysis patients
25. Soluble TNF-alpha receptors are increased in chronic renal insufficiency and haemodialysis and inhibit neutrophil priming by TNF-alpha