A novel activity of immobilized penicillin G acylase: Removal of benzyloxycarbonyl amino protecting group

Biocatalysis and Biotransformation

Volumn 18, Issue 3, 2000, Pages 253-258

  Alvaro, G ^a   Feliu, J A ^a   Caminal, G ^a   Lopez Santin, J ^a   Clapes, P ^a  

^a DEPARTMENT OF ENVIRONMENTAL CHEMISTRY   (Spain)

Author keywords

Enzymes and enzyme reactions; Hydrolysis; Peptides and polypeptides; Urethane protecting groups

Indexed keywords

AMINO ACIDS; ANTIBIOTICS; ENZYME KINETICS; ESCHERICHIA COLI; ORGANIC SOLVENTS; POLYPEPTIDES; SYNTHESIS (CHEMICAL);

AGAROSE GEL; BENZYLOXYCARBONYL AMINO PROTECTING GROUP; OLIGOPEPTIDES; PENICILLIN G ACYLASE;

ENZYME IMMOBILIZATION;

AMINO ACID; BENZYL DERIVATIVE; CARBONYL DERIVATIVE; OLIGOPEPTIDE; PENICILLIN AMIDASE; URETHAN;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; ENZYME ACTIVITY; ENZYME IMMOBILIZATION; ESCHERICHIA COLI; HYDROLYSIS; NONHUMAN;

ESCHERICHIA COLI;

EID: 0033841601     PISSN: 10242422     EISSN: None     Source Type: Journal    
DOI: 10.3109/10242420009015248     Document Type: Article

References (15)

1. Immobilization-stabilization of penicillin G acylase from E. coli
2. Enzymatic peptide synthesis in organic media. Synthesis of CCK-8 dipeptide fragments
3. Enzymatic synthesis of a CCK-8 tripeptide fragment in organic media
4. Enzymatic peptide synthesis in low water content systems: Preparative enzymatic synthesis of [Leu]- and [Met]-enkephalin derivatives
5. Penicillin acylase-catalyzed protection and deprotection of amino groups as a promising approach in enzymatic peptide synthesis
6. Aldehyde-agarose gels as activated supports for immobilization-stabilization of enzymes
7. Substrate specificity of penicillin amidase from E. coli
8. A novel enzyme, Nα-benzyloxycarbonyl amino acid urethane hydrolase IV
9. Enzymatic synthesis of a characteristic phosphorylated and glycosylated peptide fragment of the large subunit of mammalian RNA polymerase II
10. S-Phenylacetamidomethyl (Phacm): An orthogonal cysteine protecting group for Boc and Fmoc solid-phase peptide synthesis strategies
11. Protecting group strategies in organic synthesis
12. Mixed anhydrides in peptide synthesis. Influence of the solvent and the amine on the racemization of DMet residue of an enkephalin sequence
13. The use of penicillin acylase for selective N-terminal deprotection in peptide synthesis
14. Synthesis of the palmitoylated and farnesylated C-terminal lipohexapeptide of the human N-Ras protein by employing an enzymatically removable urethane protecting group
15. Enzymatic protecting group techniques