Antiplatelet and antithrombotic effect of D-003

Pharmacological Research

Volumn 42, Issue 2, 2000, Pages 137-143

  Molina, V ^a   Arruzazabala, M L ^a   Carbajal, D ^a   Mas R ^a   Valdes S ^a  

^a NATL CENTER FOR SCIENTIFIC RESEARCH   (Cuba)

Author keywords

Arterial thrombosis; Bleeding time; D 003; Platelet aggregation

Indexed keywords

ADENOSINE DIPHOSPHATE; ALIPHATIC COMPOUND; COLLAGEN; D 003; NATURAL PRODUCT; SATURATED FATTY ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY THROMBOSIS; ARTICLE; BLEEDING TIME; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; GUINEA PIG; NONHUMAN; PRIORITY JOURNAL; RAT; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION; THROMBOGENESIS;

EID: 0033841528     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1006/phrs.2000.0664     Document Type: Article

References (42)

1. Aspirin related gastrointestinal bleeders have an exaggerated bleeding time response due to aspirin use
2. European stroke prevention study. Dipyridamole and acetylsalicilic acid in the secondary prevention of stroke
3. Clinical use of glycoprotein IIb/IIIa inhibitors
4. Rash in patients receiving ticlopidine after intracoronary stent placement
5. Effect of ateromixol (policosanol) on serum lipids and lipoproteins in healthy volunteers
6. Efficacy and safety of policosanol in patients with primary hypercholesterolemia
7. Effects of policosanol in elderly hypercholesterolemic patients
8. Effects of policosanol succesive dose increases on lipid profile of patients with type II hypercholesterolemia and tolerability to treatment
9. Effects of policosanol in lowering-cholesterol levels in patients with type II hypercholesterolemia
10. One year study on the effect of policosanol (5 mg twice a day) on lipid profile in patients with type II hypercholesterolemia
11. Effect of policosanol on in vitro and in vivo rat liver microsomal lipid peroxidation
12. Effects of policosanol on platelet aggregation in rats
13. Effect of policosanol on platelet aggregation in healthy volunteers
14. Effect of policosanol on platelet aggregation in type II hypercholesterolemic patients
15. 2
16. Estudio farmacologico de la interaccion entre el policosanol y la aspirina en animales de experimentacion
17. Effect of policosanol on experimental thrombosis models
18. Biodistribution and metabolism of orally administered octacosanol in rats
19. 14C)-octacosanol in liver and muscle of rats after serial administration
20. Metabolism of octacosanol in liver and muscle of rat
21. 2, and adenosine diphosphate in collagen-induced aggregation in man and the rat
22. Comparison of the antithrombotic effects of FK633, GPIIb/IIIa antagonist and aspirin in a guinea-pig thrombosis model
23. Aggregation of blood platelets by adenosine diphosphate and its reversal
24. A new model of arterial thrombosis
25. Bleeding time in rats: A comparison of different experimental conditions
26. Models of thrombosis
27. Increased aortic thromboxane production in experimental atherosclerosis
28. A critical approach to the study of the new agents for the prevention of arterial thrombosis: A comment
29. Platelets, thrombosis, and antithrombotic therapies
30. Platelet activation mechanisms and markers in arterial thrombosis
31. Atherosclerotic plaque rupture and thrombosis
32. The effect of antithrombotics in a new model of arterial thrombosis
33. Antithrombotics in view of thrombosis models
34. Reactive oxygen metabolites and arterial thrombosis
35. Hydrogen peroxide release from human blood platelets
36. Hydrogen peroxide is an intermediate in the platelet activation cascade triggered by collagen, but not by thrombin
37. Free radical-lipid peroxidation interactions and their pathological consequences
38. Modulation of platelet function by free radicals and free radicals scavengers
39. The mechanism of the effect of aspirinon human platelets. Acetylation of a particulate fraction protein
40. Functionally thrombasthenic state in normal platelets following the administration of ticlopidine