Replacement of the carboxylic acid group of prostaglandin F(2α) with a hydroxyl or methoxy substituent provides biologically unique compounds

British Journal of Pharmacology

Volumn 130, Issue 8, 2000, Pages 1933-1943

  Woodward, D F ^a   Krauss, A H P ^a   Chen, J ^a   Gil, D W ^a   Kedzie, K M ^a   Protzman, C E ^a   Shi, L ^a   Chen, R ^a   Krauss, H A ^a   Bogardus, A ^a   Dinh, H T T ^a   Wheeler, L A ^a   Andrews, S W ^a   Burk, R M ^a   Gac, T ^a   Roof, M B ^a   Garst, M E ^a   Kaplan, L J ^a   Sachs, G ^b   Pierce, K L ^c   Regan, J W ^c   Ross, R A ^a   Chan, M F ^a   more..

^a ALLERGAN INC   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

Author keywords

FP receptor; Prostaglandin F(2 ) (PGF(2 )); Prostanoids; Radioligad binding; Uterus

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; CALCIUM ION; FLUPROSTENOL; PROSTAGLANDIN D2; PROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA DERIVATIVE; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; THROMBOXANE RECEPTOR BLOCKING AGENT; TRITIUM;

ANIMAL CELL; AORTA; ARTICLE; CAT; CELL STRAIN 3T3; CHICKEN; DRUG RECEPTOR BINDING; FIBROBLAST CULTURE; GUINEA PIG; HUMAN; HUMAN CELL; ILEUM; JUGULAR VEIN; LIGAND BINDING; LUNG PARENCHYMA; MUSCLE TONE; NONHUMAN; PRIORITY JOURNAL; RABBIT; RAT; SMOOTH MUSCLE CONTRACTION; UTERUS;

EID: 0033841265     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703462     Document Type: Article

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