A Caenorhabditis elegans type I TGFβ receptor can function in the absence of type II kinase to promote larval development

Development

Volumn 127, Issue 15, 2000, Pages 3337-3347

  Gunther, C V ^a   Georgi, L L ^a   Riddle, D L ^a  

^a UNIVERSITY OF MISSOURI   (United States)

Author keywords

Caenorhabditis elegans; Daf 1; Daf 4; Dauer; TGF ; Type I receptor

Indexed keywords

BONE MORPHOGENETIC PROTEIN RECEPTOR; GREEN FLUORESCENT PROTEIN; PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANIMAL TISSUE; ARTICLE; BODY SIZE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; ENVIRONMENT; ENZYME ACTIVITY; GENE MUTATION; GENE OVEREXPRESSION; LARVAL DEVELOPMENT; MOLECULAR EVOLUTION; MORPHOGENESIS; NEMATODE; NERVOUS SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RECEPTOR INTRINSIC ACTIVITY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TAIL;

ACTIVIN RECEPTORS, TYPE I; AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; GENE EXPRESSION; HELMINTH PROTEINS; LARVA; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, CELL SURFACE; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSGENES;

ANIMALIA; CAENORHABDITIS ELEGANS; INVERTEBRATA; NEMATODA;

EID: 0033841033     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Activation of signaling by the activin receptor complex
2. A dominant-negative receptor for type β transforming growth factors created by deletion of the kinase domain
3. The genetics of Caenorhabditis elegans
4. Ribbons 2.0
5. Genome sequence of the nematode C. elegans: A platform for investigating biology
6. Reactivity of cytosine and thymine in single-base-pair mismatches with hydroxylamine and osmium tetroxide and its application to the study of mutations
7. Truncated activin type II receptors inhibit activin bioactivity by the formation of heteromeric complexes with activin type I receptors
8. The role of the daf-8 gene in Caenorhabditis elegans dauer larva development
9. The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development
10. Daf-1, a C. elegans gene controlling dauer larva development, encodes a novel receptor protein kinase
11. The Caenorhabditis elegans dauer larva: Developmental effects of pheromone, food, and temperature
12. A pheromone-induced developmental switch in C. elegans: Temperature-sensitive mutants reveal a wild-type temperature-dependent process
13. Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo
14. Translation of the UGA triplet in vitro by tryptophan transfer RNAs
15. Crystal structure of the cytoplasmic domain of the type I TGFβ receptor in complex with FKB 12
16. Targets of TGF-β signaling in C. elegans dauer formation
17. Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
18. Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells
19. Specificity of TGFβ signaling is conferred by distinct type I receptors and their associated SMAD proteins in Caenorhabditis elegans
20. Selenocysteine tRNA([Ser]Sec) gene is ubiquitous within the animal kingdom
21. Drosophila Dpp signaling is mediated by the punt gene product: A dual ligand-binding type II receptor of the TGFβ receptor family
22. Human type II receptor for bone morphogenetic proteins (BMPs): Extension of the two-kinase receptor model to the BMPs
23. Efficient gene transfer in C. elegans: Extrachromosomal maintenance and integration of transforming sequences
24. Regulation of body length and male tail ray pattern formation of Caenorhabditis elegans by a member of the TGF-β family
25. Molecular evolution of a developmental pathway: Phylogenetic analyses of transforming growth factor-β family ligands, receptors and Smad signal transducers
26. The DAF-3 Smad protein antagonizes TGF-β-related receptor signaling in the Caenorhabditis elegans dauer pathway
27. Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor
28. Control of C. elegans larval development by neuronal expression of a TGF-β homolog
29. Amino acid preferences for specific locations at the ends of α helices
30. An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo
31. The taxonomy of developmental control in Caenorhabditis elegans
32. Caenorhabditis elegans genes sma-2, sma-3 and sma-4 define a conserved family of transforming growth factor beta pathway components
33. A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo
34. A BMP homolog acts as a dose-dependent regulator of body size and male tail patterning in Caenorhabditis elegans
35. Critical periods in the development of the Caenorhabditis elegans dauer larva
36. Characterization of type I receptors for transforming growth factor-β and activin
37. Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4
38. Evidence for parallel processing of sensory information controlling dauer formation in Caenorhabditis elegans
39. Complementation between kinase-defective and activation-defective TGF-β receptors reveals a novel form of receptor cooperativity essential for signaling
40. Mechanism of action of the TGF-β receptor