Late post-myocardial infarction induces a tetrodotoxin-resistant Na+ current in rat cardiomyocytes

Journal of Molecular and Cellular Cardiology

Volumn 32, Issue 7, 2000, Pages 1169-1179

  Alvarez, Julio L ^a   Aimond, Franck ^b   Lorente, Paco ^b   Vassort, Guy ^b  

^a INSTITUTO DE CARDIOLOGÍA Y CIRUGÍA CARDIOVASCULAR   (Cuba)

^b INSERM   (France)

Author keywords

Arrhythmia; Heart disease; Ionic channel; Lidocaine; Remodeling

Indexed keywords

TETRODOTOXIN;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CORONARY ARTERY LIGATION; ELECTROPHYSIOLOGY; HEART ARRHYTHMIA; HEART INFARCTION; HEART MUSCLE CELL; HEART REPOLARIZATION; HEART VENTRICLE REMODELING; NONHUMAN; PATCH CLAMP; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; SODIUM CURRENT;

ANIMALIA;

EID: 0033839846     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2000.1155     Document Type: Article

References (57)

1. Cellular electrophysiology in cardiac hypertrophy and failure
2. Cellular mechanisms of arrhythmias in hypertrophied and failing mycoardium
3. Ionic mechanism of action potential prolongation in ventricular myocytes from dogs with pacing-induced heart failure
4. Cellular and ionic basis of arrhythmias in postinfarction remodeled ventricular myocardium
5. Ionic basis of ventricular arrhythmias in remodeled rat heart during long-term myocardial infarction
6. Regional alteration of the transient outward current in human left ventricular septum during compensated hypertrophy
7. Heterogeneity of the early outward current in ventricular cells isolated from normal and hypertrophied rat hearts
8. 2+ current is expressed in hypertrophied adult feline left ventricular myocytes
9. 2+ channels in ventricular cells from hypertrophied rat hearts
10. 2+ channels are abnormal in genetically determined cardiomyopathic hamster hearts
11. Expression of T-type calcium current in remodeled hypertrophied left ventricle from adult rat following myocardial infarction
12. Characterization of the sodium current in single human atrial myocytes
13. + channels by batrachotoxin: Effects on gating, kinetics, and local anesthetic binding
14. +-currents in myocytes from epicardial border zone of the infarcted heart: A possible ionic mechanism for reduced excitability and postrepolarization refractoriness
15. Sodium channels in cultured cardiac cells
16. Slow currents through single sodium channels of the adult rat heart
17. + channel blockade: Multiple rest states revealed by channel interactions with disopyramide and quinidine
18. + currents in rabbit coronary myocytes
19. The saxitoxin/tetrodotoxin binding site on cloned rat brain Ila Na channels is in the transmembrane electric field
20. + channel subtypes
21. 2+ currents in atrial cells
22. Tetrodotoxin-blockade calcium currents in rat ventricular myocytes; a third type of cardiac cell sodium current
23. + channels in guinea pig ventricular myocytes
24. + channels: Slip-mode conductance
25. Myocardial infarct size and ventricular function in rats
26. Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells
27. Possible existence of transient TTX-sensitive chloride current in the membrane of isolated cardiomyocytes
28. Ca((2+))-activated Cl((-)) current can be triggered by Na((+)) current-induced SR Ca((2+)) release in rabbit ventricle
29. + channels
30. Effect of tetrodotoxin on action potentials of the conducting system in the dog heart
31. A persistent sodium current in rat ventricular myocytes
32. Novel. Ultraslow inactivating sodium current in human ventricular cardiomyocytes
33. + current in rat ventricular myocytes
34. A point mutation in domain 4-segment 6 of the skeletal muscle sodium channel produces an atypical inactivation state
35. Lidocaine block of cardiac sodium channels
36. Voltage- and use-dependent effects of lidocaine on sodium current in rat single ventricular cells
37. +-currents in ventricular myocytes form the epicardial border zone of the infarcted heart
38. Ionic currents in the somatic membrane of rat dorsal root ganglion neurons-I. Sodium currents
39. +-current in young enmbryonic heart
40. A tetrodotoxin insensitive inward sodium current in feline ventricular myocytes
41. Tetrodotoxin-insensitive sodium channels in a cardiac cell line from a transgenic mouse
42. + channels in rat dorsal root ganglia
43. + current through a nifedipine inhibited inward channel
44. Calcium channel characteristics conferred on the sodium channel by single mutations
45. Mechanisms of sodium/calcium selectivity in sodium channels probed by cysteine mutagenesis and sulfhydryl modification
46. A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons
47. Structure and function of voltage-dependent sodium channels: Comparison of brain II and cardiac isoforms
48. Cytoskeletal role in the contractile dysfunction of hypertrophied myocardium
49. Intrinsic myocyte dysfunction and tyrosine kinase pathway activation underlie the impaired wall thickening of adjacent regions during postinfarct left ventricular remodeling
50. Molecular localization of an ion-binding site within the pore of mammalian sodium channels
51. Trypsin inhibits the action of tetrodotoxin on neurones
52. Effect of sulfhydryl oxidation on ionic and gating currents associated with L-type calcium channels in isolated guinea-pig ventricular myocytes
53. 2+ channel α(1C) subunits by redox agents and hypoxia
54. A sustained inward current activated at the diastolic potential range in rabbit sino-atrial node cells
55. 2+-mediated single channel currents in guinea-pig sinoatrial node pacemaker cells