Recommendations for the categorization of germ cell mutagens

International Archives of Occupational and Environmental Health

Volumn 73, Issue 6, 2000, Pages 428-432

  Adler, I D ^a   Andrae, U ^a   Kreis, P ^b   Neumann, H G ^c   Thier, R ^d   Wild, D ^e  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

^e FEDERAL RESEARCH INSTITUTE OF NUTRITION AND FOOD   (Germany)

Author keywords

Genetic risk; Germ cell mutagens; List of MAK and BAT values

Indexed keywords

CARCINOGEN; MUTAGENIC AGENT;

ARTICLE; CHROMOSOME ABERRATION; CLASSIFICATION; GENE MUTATION; GENETIC RISK; GERM CELL; HERITABILITY;

EID: 0033839232     PISSN: 03400131     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004200000122     Document Type: Article

References (39)

1. Cytogenetic tests in mammals
2. The heritable translocation test
3. In vivo cytogenetic effects of trimethylphosphate and of tepa on bone marrow cells of male rats
4. Vorschlage zur Einstufung von Keimzellmutagenen
5. Analysis of sister chromatid exchange formation in vivo in mouse spermatogonia as a new test system for environmental mutagens
6. Somatic and germ cell effects in rats and mice after treatment with 1,3-butadiene and its metabolites, 1,2-epoxybutene and 1,2,3,4-diepoxybutane
7. Cytogenetic study of the offspring of atomic bomb survivors, Hiroshima and Nagasaki
8. Mouse models of human disease. Part II: Recent progress and future directions
9. Analysis of X-ray-induced chromosomal translocations in human and marmoset spermatogonial stem cells
10. Mutation surveillance of sentinel anomalies in Hungary, 1980-1984
11. Dominant lethal mutations in male mice
12. Induction of gene mutations in mice: The multiple endpoint approach
13. The mammalian spot test (Fellfleckentest) with mice
14. Risk estimation based on germ-cell mutations in animals
15. Transgenic mice as model systems for studying gene mutations in vivo
16. Aneuploidies and micronuclei in the germ cells of male mice of advanced age
17. An increased frequency of human sperm chromosomal abnormalities after radiotherapy
18. Perspectives in mutation epidemiology, 6: A 1983 view of sentinel phenotypes
19. Mortality in the children of atomic bomb survivors and controls
20. Current status of genetic follow-up studies in Hiroshima and Nagasaki
21. Search for mutations altering protein charge and/or function in children of atomic bomb survivors: Final report
22. Cytogenetic observations, in mouse secondary spermatocytes, on numerical and structural chromosome aberrations induced by cyclophosphamide in various stages of spermatogenesis
23. Chemotherapy induces transient sex chromosomal and autosomal aneuploidy in human sperm
24. Invited review: Prevalence of genetic and partially genetic diseases in man and the estimation of genetic risks of exposure to ionizing radiation
25. Ionizing radiation, genetic risk estimation and molecular biology: Impact and inferences
26. The micronucleus test
27. Some further observations on the sex ratio among infants born to survivors of the atomic bombings of Hiroshima and Nagasaki
28. Hiroshima and Nagasaki: A reassessment of the mutagenic effect of exposure to ionizing radiation
29. Genetic effects of the atomic bombs: A reappraisal
30. Hiroshima and Nagasaki: Three and a half decades of genetic screening
31. Measurement of DNA breakage in spermiogenic germ-cell stages of mice exposed to ethylene oxide, using an alkaline elution procedure
32. Ethylation of DNA and protamine by ethyl methanesulfonate in the germ cells of male mice and the relevance of these molecular targets to the induction of dominant lethals
33. Studies on DNA repair in early spermatid stages of male mice after in vivo treatment with methyl, ethyl, propyl, and isopropyl methanesulfonate
34. Genome surfing: Using internet-based information tools toward functional genetic studies in mouse and humans
35. A comparative genetic map of rat, mouse and human genomes
36. A micronucleus method for detection of meiotic micronuclei in male germ cells of mammals
37. 1) of atomic bomb survivors, 1946-1985