Withdrawal of enzyme replacement therapy in Gaucher's disease

British Journal of Haematology

Volumn 110, Issue 2, 2000, Pages 488-492

  Elstein, D ^a   Abrahamov, A ^a   Hadas Halpern, I ^a   Zimran, A ^a  

^a SHAARE ZEDEK MEDICAL CENTER   (Israel)

Author keywords

Ethics; Gaucher's disease; Treatment withdrawal

Indexed keywords

ALGLUCERASE; IMIGLUCERASE;

ADOLESCENT; ADULT; ANEMIA; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE EXACERBATION; DRUG WITHDRAWAL; ENZYME REPLACEMENT; FEMALE; GAUCHER DISEASE; HEMOGLOBIN DETERMINATION; HUMAN; LIVER SIZE; MAINTENANCE THERAPY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SPLEEN SIZE; THROMBOCYTOPENIA;

ADOLESCENT; ADULT; CHILD, PRESCHOOL; ENZYMES; FEMALE; GAUCHER DISEASE; HEMOGLOBINS; HEPATOMEGALY; HUMANS; MALE; MIDDLE AGED; PLATELET COUNT; SEVERITY OF ILLNESS INDEX; SPLENOMEGALY; TREATMENT OUTCOME; TREATMENT REFUSAL;

EID: 0033836414     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2000.02177.x     Document Type: Article

References (11)

1. Replacement therapy for inherited enzyme deficiency: Macrophage-targeted glucocerebrosidase for Gaucher's disease
2. Enzyme replacement therapy for Gaucher's disease
3. Retroviral transfer of the glucocerebrosidase gene into CD34+ cells from patients with Gaucher disease: In vivo detection of transduced cells without myeloablation
4. Echocardiographic assessment of pulmonary hypertension in Gaucher's disease
5. Cessation of enzyme replacement therapy (ERT) in Gaucher disease type I
6. A practical approach to diagnosis and management of Gaucher's disease
7. The Gaucher registry: Clinical response after 60 months of enzyme replacement therapy (ERT)
8. Prediction of severity of Gaucher's disease by identification of mutations at DNA level
9. Gaucher disease: Clinical, radiologic, and genetic features of 53 patients
10. Low-dose enzyme replacement therapy for Gaucher's disease: Effects of age, sex, genotype and clinical features on response to treatment
11. Children with type I Gaucher disease: Growing into adulthood with and without enzyme therapy