Apoptosis in bladder carcinomas detected with monoclonal antibody to single-stranded DNA: Relation to cell cycle regulators and survival

Urology

Volumn 56, Issue 3, 2000, Pages 516-520

  Korkolopoulou, Penelope ^c   Konstantinidou, Anastasia E ^a   Christodoulou, Panagiota ^b   Patsouris, Efstratios ^a   Thomas Tsangli, Euphemia ^b   Kapralos, Panagiotis ^b   Davaris, Panagiotis ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b Asklepeion Voula Hospital   (Greece)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

KI 67 ANTIGEN; PROTEIN P21; PROTEIN P27; PROTEIN P53; SINGLE STRANDED DNA;

ADULT; AGED; APOPTOSIS; ARTICLE; BLADDER CARCINOMA; CANCER INVASION; CANCER SURVIVAL; CELL CYCLE; CELL PROLIFERATION; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TRANSITIONAL CELL CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; ANTIBODIES, MONOCLONAL; APOPTOSIS; CARCINOMA, TRANSITIONAL CELL; CELL CYCLE PROTEINS; CELL DIVISION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLINS; DNA FRAGMENTATION; DNA, SINGLE-STRANDED; FEMALE; HUMANS; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; NEOPLASM PROTEINS; SURVIVAL ANALYSIS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; URINARY BLADDER NEOPLASMS;

EID: 0033835339     PISSN: 00904295     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0090-4295(00)00653-1     Document Type: Article

References (29)

1. Wyllie A.H. Apoptosis. Br J Cancer. 67:1993;205-208.
2. El-Deiry W.S., Tokino T., Velculescu V.E., et al. WAF1, a potential mediator of p53 tumor suppression. Cell. 75:1993;817-825.
3. Kastan M.B., Ohyekwere P., Sidransky D., et al. Participation of p53 protein in the cellular response to DNA damage. Cancer Res. 51:1991;6304-6311.
4. Katayose Y., Kim M., Amol N.S., et al. Promoting apoptosis a novel activity associated with the cyclin-dependent kinase inhibitor p27 . Cancer Res. 57:1997;5441-5445.
5. Kip1 overexpression causes apoptotic death of mammalian cells. Oncogene. 15:1997;2991-2997.
6. Lipponen P.K., Eskelinen M.J., Jauhiainen K., et al. Independent clinical, histological and quantitative prognostic factors in transitional cell bladder tumours, with special reference to mitotic frequency. Int J Cancer. 51:1993;396-403.
7. Korkolopoulou P., Christodoulou P., Kapralos P., et al. The role of p53, MDM2 and c-erbB-2 oncoproteins, epidermal growth factor receptor and proliferation markers in the prognosis of urinary bladder cancer. Pathol Res Pract. 193:1997;767-775.
8. WAF1/Cip1 expression on tumor progression in bladder cancer. J Natl Cancer Inst. 90:1998;1072-1079.
9. Kip1 expression correlates with tumor grade and with reduced disease-free survival in primary superficial bladder cancers. Cancer Res. 59:1999;3245-3250.
10. Lipponen P.K., Aaltomaa S. Apoptosis in bladder cancer as related to standard prognostic factors and prognosis. J Pathol. 173:1994;333-339.
11. King E.D., Matteson J., Jacobs S.C., et al. Incidence of apoptosis, cell proliferation and bcl-2 expression in transitional cell carcinoma of the bladder association with tumor progression . J Urol. 155:1996;316-320.
12. Szende B., Juhasz E., Lapis K., et al. Inhibition of two-step urinary bladder carcinogenesis by the somatostatin analogue RC-160. Urol Res. 20:1992;383-386.
13. Grignon D.J. Neoplasms of the urinary bladder. Bostwick D.G., Eble J.N. Urologic Surgical Pathology. 1997;252-253 Mosby, St Louis.
14. Hermanek P., Sobin L.H.:. TNM Classification of Malignant Tumours. 4th ed. 1992;Springer, Berlin.
15. Epstein J.I., Amin M.B., Reuter V.R., et al. The World Health Organization/International Society of Urological Pathology Consensus classification of urothelial (transitional cell) neoplasms of the urinary bladder. Am J Surg Pathol. 22:1998;1435-1448.
16. Norton A.J., Jordon S., Yeomans P. Brief, high-temperature heat denaturation (pressure cooking) a simple and effective method of antigen retrieval for routinely processed tissues . J Pathol. 173:1994;371-379.
17. Frankfurt O.S., Robb J.A., Sugarbaker E.V., et al. Apoptosis in breast carcinomas detected with monoclonal antibody to single-stranded DNA relation to bcl-2 expression, hormone receptors and lymph node metastases . Clin Cancer Res. 3:1997;465-471.
18. Lipponen P., Aaltomaa S., Eskelinen M., et al. Expression of p21 (WAF1/Cip1) protein in transitional cell bladder tumours and its prognostic value. Eur Urol. 34:1998;237-243.
19. Kuczyk M.A., Machtens S., Bokemeyer C., et al. Prognostic value of p27/Kip1 and p21(WAF1/Cip1) protein expression in muscle invasive bladder cancer. Oncol Rep. 6:1999;687-693.
20. Columbano A. Cell death current difficulties in discriminating apoptosis from necrosis in the context of pathological processes in vivo . J Cell Biochem. 58:1995;181-190.
21. Grasl-Kraupp B., Ruttkay-Nedecky B., Koudelka M., et al. In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis and autolytic cell death a cautionary note . Hepatology. 21:1995;1465-1468.
22. Frankfurt O.S., Robb J.A., Sugarbaker E.V., et al. Monoclonal antibody to single-stranded DNA is a specific and cellular marker of apoptosis. Exp Cell Res. 226:1996;387-397.
23. Earnshaw W.C. Nuclear changes in apoptosis. Curr Opin Cell Biol. 7:1995;337-343.
24. Bell D.A., Morrison B. The spontaneous apoptotic cell death of normal human lymphocytes in vitro the release of, and immunoproliferative response to, nucleosomes in vitro . Clin Immunol Immunopathol. 60:1991;13-26.
25. Keegan P.E., Lunec J., Neal D.E. p53 and p53-regulated genes in bladder cancer review . Br J Urol. 82:1998;710-720.
26. Kip1 and apoptosis in tumor cells on the overall survival of patients with non-early stage gastric carcinoma. Cancer. 85:1999;1711-1718.
27. Gorospe M., Cirielli C., Wang X., et al. p21 (WAF1/Cip1) protects against p53-mediated apoptosis of human melanoma cells. Oncogene. 14:1997;929-936.
28. Frankfurt O.S., Seckinger D., Sugarbaker E.V. Pleiotropic drug resistance and survival advantage in leukemic cells with diminished apoptotic response. Int J Cancer. 59:1994;217-224.
29. Pryor J.P. Factors influencing the survival of patients with transitional cell tumours of the urinary bladder. Br J Urol. 45:1973;586-591.