Effect of CD40 ligand and other immunomodulators on Pneumocystis carinii infection in rat model

Microbial Pathogenesis

Volumn 29, Issue 3, 2000, Pages 187-190

  Oz, Helieh S ^a   Hughes, Walter T ^b   Rehg, Jerold E ^b   Thomas, Elaine K ^c  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c AMGEN INC   (United States)

Author keywords

Bryostatin 1; CD40L; FLT3L; IL 15; P. carinii; PCP

Indexed keywords

BRYOSTATIN 1; DEXAMETHASONE; FLT3 LIGAND; GLYCOPROTEIN GP 39; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT INTERLEUKIN 15;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; NONHUMAN; PNEUMOCYSTIS CARINII; PNEUMOCYSTIS PNEUMONIA; PRIORITY JOURNAL; RAT; TREATMENT OUTCOME;

ANIMALIA; MURINAE; PNEUMOCYSTIS CARINII; PROTOZOA;

EID: 0033834761     PISSN: 08824010     EISSN: None     Source Type: Journal    
DOI: 10.1006/mpat.2000.0374     Document Type: Article

References (13)

1. Experimental animal models
2. Effect of sex and dexamethasone dose on the experimental host for Pneumocystis carinii
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4. Provocation of infection due to Pneumocystis carinii by cyclosporin A
5. Recombinant CD40 ligand exerts potent biologic effects on T cells
6. CD40 ligand is required for resolution of Pneumocystis carinii pneumonia in mice
7. Modulation of spontaneous Pneumocystosis in mice by administration of CD40L trimer
8. Human immunodeficiency virus type 1 infection of human macrophages modulates the cytokine response to Pneumocystis carinii
9. Proliferative and cytokine responses to a major surface glycoprotein of Pneumocystis carinii
10. A potential role for interleukin-15 in the regulation of human natural killer cell survival
11. Interleukin-15 up-regulates interleukin-2 receptor alpha chain but down-regulates its own high-affinity binding sites on human T and B cells
12. IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice
13. Successful treatment of murine melanoma with bryostatin 1