Genotoxic and mono-oxygenase system effects of the fungicide maneb

Archives of Toxicology

Volumn 74, Issue 7, 2000, Pages 415-420

  Bertini, Simone ^b   Del Carratore, Renata ^c   Giorgi, Mario ^a   Bronzetti, Giorgio ^c   Della Croce, Clara ^a  

^a Dipartimento di Clinica Veterinaria   (Italy)

^b Istituto di Ispezione degli Alimenti di Origine Animale   (Italy)

^c CNR   (Italy)

Author keywords

Cytochrome P 450; Genotoxicity; Maneb; Saccharomyces cerevisiae; Z Yeast

Indexed keywords

2 IMIDAZOLIDINETHIONE; CYTOCHROME P450; FUNGICIDE; MANEB; UNSPECIFIC MONOOXYGENASE;

ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENOTOXICITY; IMMUNOBLOTTING; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; RAT; SACCHAROMYCES CEREVISIAE;

ANILINE HYDROXYLASE; ANIMAL; BIOTRANSFORMATION; BLOTTING, WESTERN; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; FUNGICIDES, INDUSTRIAL; GENE CONVERSION; MANEB; MICROSOMES, LIVER; MUTAGENICITY TESTS; MUTAGENS; RATS; RATS, WISTAR; SACCHAROMYCES CEREVISIAE; SUPPORT, NON-U.S. GOV'T;

ANIMALIA; SACCHAROMYCES CEREVISIAE;

EID: 0033834150     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040000152     Document Type: Article

References (37)

1. Toxicity of dithiocarbamates and their fate in warmblooded animals
2. Yeast cytochrome P-450 catalyzing lanosterol 14 alpha-demethylation. II. Lanosterol metabolism by purified P-450 (14) DM and by intact microsomes
3. Sister-chromatid exchanges and chromosomal aberrations in chick embryos after treatment with the fungicide maneb
4. Studies on the mechanism of nabam- and zineb-induced inhibition of the hepatic microsomal monooxygenases of the male rat
5. Perinatal toxicity of maneb, ethylenthiourea, and ethylene bisisotiocyanate sulfide in rodents
6. The influence of tetramethylthiuram disulfide on the estrous cycle and genital function of animals when inhalated
7. Cytochrome P-450 factors determining synthesis in strain D7 of Saccharomyces cerevisiae. An alternative system to microsomal assay
8. Mutagenicity of diallate, sulfallate and triallate and relationship between structure and mutagenic effects of carbamates used widely in agricolture
9. Zineb: Effect on rat monooxygenase system and genotoxicity in yeast
10. Studies on the metabolism of the fungicidal ethylenbisdithiocarbamates, maneb, zineb and nabam. V. The toxicology of breakdown products
11. Chronic exposure to the fungicide maneb may produce symptoms and signs of CNS manganese intoxication
12. Human cytochromes P-450: Problems and prospects
13. Acute intoxication due to exposure to maneb and zineb
14. Advances in sample preparation, electrophoretic separation and detection methods for cytochrome enzymes
15. 2 dithiocarbamates
16. Examination of the 'in vivo' metabolism of maneb and zineb to ethylenethiourea (ETU) in mice
17. Manganese toxicity in humans and experimental animals
18. Monoclonal antibodies to ethanol induced rat liver cytochrome P-450 that metabolise aniline and nitrosamines
19. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
20. Studies of teratogenic effects of the dithiocarbamates maneb, mancozeb and propineb
21. Genetic and biochemical studies on a commercial preparation of atrazine
22. Further mutagenicity studies on pesticides in bacterial reversion assay system
23. The P-450 superfamily: Update on new sequences, gene mapping, accession numbers, early trivial names of enzymes and nomenclature
24. The carbon monoxide-binding pigment of liver microsomes. II. Solubilization, purification, and properties
25. Stability of drug metabolizing enzymes during the incubation conditions of the liver microsomal assay with non-induced and induced mouse liver S-9 fraction
26. Role of phase II enzymes in the bioactivation of 1: 4-dichlorobenzene and 1: 4-dibromobenzene
27. Rapid brain uptake of manganese (II) across the blood-brain barrier
28. Maneb
29. A survey on the mutagenicity of various pesticides
30. Cytochromes P-450 in rats: Structures, functions, properties and relevant human forms
31. Electrophoretic transfer of proteins from gels to nitrocellulose sheets: Procedure and same application
32. Metodologie biochimiche
33. A yeast strain for simultaneous detection of induced mitotic crossing over, mitotic gene conversion and reverse mutation