Modulation of tumour necrosis factor production with desmuramyldipeptide analogues

Pflugers Archiv European Journal of Physiology

Volumn 440, Issue SUPPL. 5, 2000, Pages

  Simčič, Sača ^a   Wraber, Branka ^a   Sollner, Marija ^a   Urleb, Uroš ^a   Gobec, Stanislav ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Desmuramyldipeptide; Immunomodulation; Mononuclear cells; Phorbol myristate acetate; Tumour necrosis factor

Indexed keywords

4 DIETHYLPHOSPHONYL 2 [[(5 PHTHALIMIDOPENTANOYL)ALANYL]AMINO]BUTANOIC ACID; 4 DIETHYLPHOSPHONYL 2 [[N [5 (1 ADAMANTANECARBOXAMIDO)PENTANOYL]ALANYL]AMINO]BUTANOIC ACID; 7 OXOOCTANOYL ALANYL DEXTRO ISOGLUTAMINE; IMMUNOMODULATING AGENT; IONOMYCIN; LIPOPOLYSACCHARIDE; MURAMYL DIPEPTIDE DERIVATIVE; MUROCTASIN; N (5 PHTHALIMIDOPENTANOYL) DEXTRO ALANYL DEXTRO ISOGLUTAMINE; N (5 PHTHALIMIDOPENTANOYL)ALANYL DEXTRO ISOGLUTAMINE; N [(4 PHTHALIMIDOBUTYL)METHYLPHOSPHONYL]ALANYL DEXTRO ISOGLUTAMINE; N [2 (2 PHTHALIMIDOETHOXY)ACETYL]ALANYL DEXTRO GLUTAMIC ACID; N [2 [2 (1 ADAMANTANECARBOXAMIDO)ETHOXY]ACETYL]ALANYL DEXTRO ISOGLUTAMINE; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; 4 DI ETHYLPHOSPHONYL 2 [[N [5 (1 ADAMANTANECARBOXAMIDO)PENTANOYL] LEVO ALANYL]AMINO]BUTANOIC ACID; 4 DIETHYLPHOSPHONYL 2 [[(5 PHTHALIMODOPENTANOYL) LEVO ALANYL]AMINO]BUTANOIC ACID; 7 OXOOCATANOYL LEVO ALANYL DEXTRO ISOGLUTAMINE; DESMURAMYLDIPEPTIDE ANALOG; MURAMYL DIPEPTIDE; N (5 PHTHALMIDOPENTANOYL) DEXTRO ALANYL DEXTRO ISOGLUTAMINE; N (5 PHTHALMIDOPENTANOYL) LEVO ALANYL DEXTRO ISOGLUTAMINE; N [(4 PHTHALIMIDOBUTYL)METHYLPHOSPHONYL] LEVO ALANYL DEXTRO ISOGLUTAMINE; N [2 (2 PHTHALIMIDOETHOXY)ACETYL] LEVO ALANYL DEXTRO GLUTAMIC ACID; N [2 [2 (1 ADAMANTANECARBOXAMIDO)ETHOXY]ACETYL] LEVO ALANYL DEXTRO ISOGLUTAMINE; PEPTIDE DERIVATIVE;

CELL KINETICS; CELL STIMULATION; CONFERENCE PAPER; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; DRUG ACTIVITY; DRUG EFFECT; HUMAN; HUMAN CELL; IMMUNOMODULATION; MONONUCLEAR CELL; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; ARTICLE; DRUG SYNTHESIS; IN VITRO STUDY; KINETICS; PERIPHERAL BLOOD MONONUCLEAR CELL; UPREGULATION;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; ADJUVANTS, IMMUNOLOGIC; DRUG COMBINATIONS; HUMANS; IONOMYCIN; IONOPHORES; MONOCYTES; TETRADECANOYLPHORBOL ACETATE; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033833904     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (8)

1. Circulating interleukin-1 and tumor necrosis factor in septic shock and experimental endotoxin fever
2. Novel Biological Response Modifiers Derived from Thalidomide
3. Therapeutic effects of LK 423, a phthalimido-desmuramyl-dipeptide compound, on dextran sulfate sodium-induced colitis in rodents through restoring their interleukin-10 producing capacity
4. Influence of synthetic adjuvants on nonspecific resistance to infections
5. Differential regulation by thalidomide and dexamethasone of cytokine expression in human PBMC
6. Differences in interleukin 1 (IL-1), IL-6, tumor necrosis factor and IL-1 receptor antagonist production by human monocytes stimulated with muramyl dipeptide (MDP) and its stearoyl derivative, romurtide
7. The role of cytokines in gram-positive bacterial shock
8. Specific Binding of Soluble Peptidoglycan and Muramyldipeptide to CD14 on Human Monocytes