Transformed target cell-derived superoxide anions drive apoptosis induction by myeloperoxidase

Redox Report

Volumn 5, Issue 4, 2000, Pages 207-214

  Engelmann, I ^a   Dormann, S ^a   Saran, M ^b   Bauer, G ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBENZOIC ACID; CATALASE; DIMETHYL SULFOXIDE; HYDRAZIDE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; HYPOCHLOROUS ACID; MYELOPEROXIDASE; SUPEROXIDE; SUPEROXIDE DISMUTASE; TAURINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DENSITY; CELL TRANSFORMATION; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; NONHUMAN; ONCOGENE H RAS; ONCOGENE SRC; PRIORITY JOURNAL; RAT; TARGET CELL;

ANIMALIA;

EID: 0033833632     PISSN: 13510002     EISSN: None     Source Type: Journal    
DOI: 10.1179/135100000101535762     Document Type: Article

References (45)

1. Insights into myeloperoxidase biosynthesis from its inherited deficiency
2. Biosynthesis and processing of myeloperoxidase: A marker of myeloid cell differentiation
3. Myeloperoxidase: A key regulator of neutrophil oxidant production
4. Myeloperoxidase
5. 2 and chloride
6. Influence of superoxide on myeloperoxidase kinetics measured with a hydrogen peroxide electrode
7. Superoxide enhances hypochlorous acid production by stimulated human neutrophils
8. Inside the neutrophil phagosome: Oxidants, myeloperoxidase, and bacterial killing
9. Phagocytic killing of microorganisms by radical processes: Consequences of the reaction of hydroxyl radicals with chloride yielding chlorine atoms
10. Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent
11. Mechanism of disproportionation of superoxide
12. Neutrophil oxygen reduction: The enzymes and the products
13. Hydroxyl radical generation by polymorphonuclear leukocytes measured by electron spin resonance spectroscopy
14. Spin trapping evidence for myeloperoxidase-dependent hydroxyl radical formation by human neutrophils and monocytes
15. Free hydroxyl radicals are formed on reaction between the neutrophil-derived species superoxide anion and hypochlorous acid
16. Neutrophil-mediated tumor cell cytotoxicity: Role of the peroxidase system
17. Cytotoxicity for tumor cells of cationic proteins from human neutrophil granules
18. 2-halide system in concanavalin A-induced tumor cell killing by human neutrophils
19. Cytolysis of B-16 melanoma tumor cells mediated by the myeloperoxidase and lactoperoxidase system
20. Induction of reactive oxygen intermediates in human monocytes by tumor cells and their role in spontaneous monocyte cytotoxicity
21. Mitogenic signalling by oxidants in Ras-transformed fibroblasts
22. Cell transformation by the superoxide-generating oxidase MoxI
23. Regulation of reactive oxygen species generation in fibroblasts by rac 1
24. The transformation-suppressive function is lost in tumorigenic cells and is restored upon transfer of a suppressor gene
25. Sensitivity of transformed fibroblasts for intercellular induction of apoptosis is determined by their transformed phenotype
26. TGF-β-treated normal fibroblasts eliminate transformed fibroblasts by induction of apoptosis
27. Detection of DNA strand breaks in individual apoptotic cells by the in-situ terminal deoxynucleotidyl transferase and nick translation assays
28. Inhibition of myeloperoxidase by benzoic acid hydrazides
29. Mechanisms of inactivation of myeloperoxidase by 4-aminobenzoic acid hydrazide
30. Transient and steady-state kinetics of the oxidation of substituted benzoic acid hydrazides by myeloperoxidase
31. Oxidative modification and nitration of human low-density lipoproteins by the reaction of hypochlorous acid with nitrite
32. Oxygen radicals acting as chemical messengers: A hypothesis
33. 2 and NO: How far can either radical, or any specific reaction product, transmit a message under in vivo conditions?
34. Capsaicin inhibits preferentially the NADH oxidase and growth of transformed cells in culture
35. A circulating form of NADH oxidase activity responsive to the antitumor sulfonylurea n-4-(methylphenylsulfonyl)-N -(4-chlorophenyl)urea (LY 181984) specific to sera from cancer patients
36. Elimination of transformed cells by normal cells: A novel concept for the control of carcinogenesis
37. Reactive oxygen species act both at TGF-β dependent and -independent steps during induction of apoptosis of transformed cells by normal cells
38. Clinical manifestation of myeloperoxidase deficiency
39. Does a relationship exist between neutrophil myeloperoxidase deficiency and the occurrence of neoplasms?
40. Depressed neutrophil-mediated tumor cell cytotoxicity in subjects affected by hereditary myeloperoxidase deficiency and secondary neoplasia
41. Immunohistochemical and genetic evidence of myeloperoxidase involvement in multiple sclerosis
42. Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions
43. Catalase, myeloperoxidase and hydrogen peroxide in cystic fibrosis
44. New mechanism for glomerular injury. Myeloperoxidase-hydrogen peroxide-halide system
45. Target cell-derived superoxide anions cause efficiency and selectivity of intercellular induction of apoptosis