Broad-spectrum sunscreens offer protection against urocanic acid photoisomerization by artificial ultraviolet radiation in human skin

Journal of Investigative Dermatology

Volumn 115, Issue 3, 2000, Pages 421-426

  Van Der Molen, Renate G ^a   Out Luiting, Coby ^b   Driller, Hansjürgen ^c   Claas, Frans H J ^d   Koerten, Henk K ^a   Mommaas, A Mieke ^a,b  

^a Center for Electron Microscopy   (Netherlands)

^b Department of Dermatology Leiden ^*  (Netherlands)

^c MERCK KGAA   (Germany)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Immunoprotection; MECLR; Titanium dioxide

Indexed keywords

SUNSCREEN; UROCANIC ACID;

ADULT; ARTICLE; CLINICAL ARTICLE; EPIDERMIS CELL; FEMALE; HUMAN; IMMUNE RESPONSE; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; ISOMERISM; MALE; PRIORITY JOURNAL; RADIATION EXPOSURE; ULTRAVIOLET RADIATION;

EID: 0033832402     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2000.00074.x     Document Type: Article

References (29)

1. Ultraviolet-light induced alterations in urocanic acid in vivo
2. The metabolism and function of urocanic acid in skin
3. Sunscreen protection of contact hypersensitivity responses from chronic solar-simulated ultraviolet irradiation corrrelates with the absorption spectrum of the sunscreen
4. Broad-spectrum sunscreens provide greater protection against ultraviolet-radiation-induced suppression of contact hypersensitivity to a recall antigen in humans
5. Mechanisms of immune suppression by ultraviolet irradiation in vivo. I. Evidence for the existence of a unique photoreceptor in skin and its role in photoimmunology
6. Urocanic acid isomers: Relation to body site, pigmentation, stratum corneum thickness and photosensitivity
7. The UV waveband dependencies in mice differ for the suppression of contact hypersensitivity delayed-type hypersensitivity and cisurocanic acid formation
8. Photocarcinogenesis. Mechanisms, models and human health implications. Subsection: Sunscreens and photocarcinogenesis: An objective assessment
9. Photoprotection: Sunscreens and the immunomodulatory effects of UV irradiation
10. A role for neuropeptides in UVB-induced systemic immunosuppression
11. Sunscreens and vitamin E provide some protection to the skin immune system from solar-simulated UV radiation
12. Differential suppression of the human mixed epidermal cell lymphocyte reaction (MECLR) and mixed lymphocyte reaction (MLR) by cisurocanic acid
13. Differential effects of sunscreens on UVB-induced immunomodulation in humans
14. A non-invasive chamber sampling technique for HPLC analysis of human epidermal urocanic acid isomers
15. Investigating the red shift between in vitro and in vivo urocanic acid photoisomerization action spectra
16. Prolonged increase of cis-urocanic acid levels in human skin and urine after single total-body ultraviolet exposures
17. Photoisomerization spectrum of urocanic acid in human skin in vitro: Effects of simultaed solar and artificial ultraviolet radiation
18. Sunscreens with broad-spectrum absorption decrease the trans to cis photoisomerization of urocanic acid in human stratum corneum after multiple UV light exposures
19. Immunologic unresponsiveness induced by ultraviolet radiation
20. Urocanic acid binds to GABA but not to histamine (H-1, H-2, or H-3) receptors
21. Urocanic acid photochemistry and photobiology
22. Z/E photoisomerization of urocanic acid
23. Differential photoimmunoprotection by sunscreen ingredients is unrelated to epidermal cis urocanic acid formation in hairless mice
24. Tanning in human skin types II and III offers modest photoprotection against erythema
25. Tape stripping of human stratum corneum yields cell layers that originate from various depths because of furrows in the skin
26. Sunscreens offer the same UVB protection factors for inflammation and immunosuppression in the mouse
27. The effects of UVA-I (340-400 nm) UVA-II (320-340 nm) and LWA-I+II on the photoisomerization of urocanic acid in vivo
28. Immune aspects of sunscreens
29. Photoprotection from UVR-induced immunosuppression