Myocyte cytoskeletal disorganization and right heart failure in hypoxia-induced neonatal pulmonary hypertension

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 279, Issue 3 48-3, 2000, Pages

  Lemler, Matthew S ^a   Bies, Roger D ^a   Frid, Maria G ^a   Sastravaha, Amornrate ^a   Zisman, Lawrence S ^a   Bohlmeyer, Teresa ^a   Gerdes, A Martin ^b   Reeves, John T ^a   Stenmark, Kurt R ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF SOUTH DAKOTA   (United States)

Author keywords

Cadherin; Cor pulmonale; Costameres; Cytoskeleton; Desmin; Intercalated disks; Metavinculin; Tubulin; Vinculin

Indexed keywords

CADHERIN; CYTOSKELETON PROTEIN; DESMIN; METAVINCULIN; UNCLASSIFIED DRUG; VIMENTIN; VINCULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATTLE; CONTROLLED STUDY; CYTOSKELETON; CYTOSOL; ECHOCARDIOGRAPHY; HEART MUSCLE CELL; HEART RIGHT VENTRICLE FAILURE; HEART VENTRICLE REMODELING; HEMODYNAMICS; HISTOPATHOLOGY; HYPOBARISM; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; LUNG ARTERY PRESSURE; MALE; MICROSCOPY; NEWBORN; NEWBORN HYPOXIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PULMONARY HYPERTENSION; WESTERN BLOTTING;

EID: 0033830678     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2000.279.3.h1365     Document Type: Article

References (61)

1. Pulmonary hypertension and right ventricular hypertrophy in cattle at high altitude
2. The heart and development
3. Immunolocalization of metavinculin in human smooth and cardiac muscles
4. Effects of acute preload and afterload stress on myocardial function in newborn and adult sheep
5. A 5' dystrophin duplication mutation causes membrane deficiency of a-dystrglycan in a family with X-linked cardiomyopathy
6. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
7. Chicken vinculin and meta-vinculin are derived from a single gene by alternative splicing of a 207-base pair exon unique to meta-vinculin
8. Chronic progressive overload of the cat right ventricle
9. Vimentin mRNA location changes during muscle development
10. Progressive loss of vasodilator response component of pulmonary hypertension in neonatal calves exposed to 4,570 m
11. Formation of binucleated cardiac myocytes in rat heart: Cytoskeletal organization
12. The pattern of desmin filaments in myocardial disarray
13. Multiple phenotypically distinct smooth muscle cell populations exist in the adult and developing bovine pulmonary arterial media in vivo
14. The importance of intermediate filaments in the adaptation of tissues to mechanical stress: Evidence from gene knockout studies
15. Structural remodeling of cardiac myocytes from patients with chronic ischemic heart disease
16. Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-biphosphate
17. The involvement of adherens junction components in myofibrillogenesis in cultured cardiac myocytes
18. Desmin and vimentin coexist at the periphery of the myofibril Z disk
19. Generation of a stable, posttranslationally modified microtubule array is an early event in myogenic differentiation
20. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques
21. Role of microtubules in myocyte contractile dysfunction during cardiac hypertrophy in the rat
22. F-actin binding site masked by the intramolecular association of vinculin head and tail domains
23. Myocardial degeneration in congenital heart disease. Comparison of morphologic findings in young and old patients with congenital heart disease associated with muscular obstruction to right ventricular outflow
24. An additional exon in the human vinculin gene specifically encodes metavinculin-specific difference peptide
25. Postnatal development of peptidernergic innervation of the canine heart
26. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
27. Formation of binucleated cardiac myocytes in rat heart: Cytoskeletal organization
28. Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development
29. N-cadherin-catenin interaction: Necessary component of cardiac cell compartmentalization during early vertebrate development
30. Dilated cardio-myopathy associated with deficiency of the cytoskeletel protein metavinculin
31. Identification, tissue specific expression, and subcellular localization of the 71- and 80-kDa forms of myotonic dystrophy kinase protein
32. The neonatal heart has a relatively high content of total collagen and type I collagen, a condition that may explain a less compliant state
33. Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart
34. Pathogenesis of ventricular hypertrophy
35. Pulmonary vasodilation with structurally altered pulmonary vessels and pulmonary hypertension
36. Immunofluorescent localization of desmin and vimentin in developing cardiac muscle of syrian hamster
37. Immunofluorescent studies on Z-line-associated protein in cultured cardiomyocytes from neonatal hamsters
38. Biochemical determination of tubulin-microtubule equilibrium in cultured cells
39. A vinculin-containing cortical lattice in skeletal muscle: Transverse lattice elements ('costameres') mark sites of attachment between myofibrils and sarcolemma
40. Spatiotemporal relation between gap junctions and fascia adherens junctions during postnatal development of human ventricular myocardium
41. Growth of the fetal calf and its arterial pressure, blood gases, and hematological data
42. Circulatory changes following birth of the calf and the effect of hypoxia
43. Physiological effects of high altitude on the pulmonary circulation
44. Fetal lamb ventricles respond differently to filling and arterial pressures and to in utero ventilation
45. Impairment of the myocardial ultrastructure and changes of the cytoskeleton in dilated cardiomyopathy
46. Distinct molecular phenotypes in murine cardiac muscle development, growth, and hypertrophy
47. Abnormalities of contractile structures in viable myocytes of the failing heart
48. Left and right ventricular myocardial morphometry in fetal, neonatal, and adult sheep
49. The extracellular matrix in human cardiac tissue. Vimentin, laminin, and fibronectin
50. Severe pulmonary hypertension and arterial adventitial changes in newborn calves at 4,300 m
51. Cytoskeletal role in the contractile dysfunction of cardiocytes from hypertrophied and failing right ventricles
52. Developmental changes in myocardial contractile reserve in the lamb
53. Null mutation in the desmin gene gives rise to a cardiomyopathy
54. Intermediate filament and associated proteins in the human heart: An immunofluoresence study of normal and pathological hearts
55. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
56. Cytoskeletal role in the contractile dysfunction of hypertrophied myocardium
57. Chronic pressure overload cardiac hypertrophy and failure in guinea pigs: Cytoskeletal remodeling
58. Chronic pressure overload cardiac hypertrophy and failure in guinea pigs: Intercalated disk remodeling
59. Regulation of post-translationally modified microtuble populations during neonatal development
60. High altitude induced pulmonary hypertension in normal cattle
61. Influence of altitude and age on pulmonary arterial pressure in cattle