Platelet cryopreservation using second-messenger effectors and low-dose (2%) dimethyl sulfoxide. In vitro evaluation of post-thawing platelet activity with the platelet function analyzer

Haematologica

Volumn 85, Issue 8, 2000, Pages 885-887

  Borzini, P ^a   Lazzaro, A ^a   Mazzucco, L ^a   Connor, R ^a   Schiavo, J ^a   Siena, S ^a  

^a C Arrigo Children's Hospital   (Italy)

Author keywords

Platelet cryopreservation

Indexed keywords

ADENOSINE; ADENOSINE DIPHOSPHATE; ADRENALIN; AMILORIDE; CYCLIC AMP; CYCLIC GMP; DIMETHYL SULFOXIDE; NITROPRUSSIDE SODIUM; THROMBOSOL; UNCLASSIFIED DRUG;

ANALYZER; ARTICLE; CELL INTERACTION; CRYOPRESERVATION; ENDOTHELIUM CELL; HEMOSTASIS; HUMAN; HUMAN CELL; SECOND MESSENGER; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION;

BLOOD PLATELETS; BLOOD PRESERVATION; CRYOPRESERVATION; CRYOPROTECTIVE AGENTS; DIMETHYL SULFOXIDE; HUMAN; PLATELET FUNCTION TESTS; SECOND MESSENGER SYSTEMS;

EID: 0033830457     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Evaluation of four different methods for platelet freezing. In vitro and in vivo studies
2. Cryopreservation of single-donor platelets with a reduced dimethyl sulfoxide concentration by addition of second-messenger effectors: Enhanced retention of in vitro activity
3. Enhanced circulatory parameters of human platelets cryopreserved with second-messenger effectors: An in vivo study of 16 volunteer platelet donors
4. Enhanced retention of in vitro activity of platelets from recombinant human thrombopoietin-treated patients following long-term cryopreservation with platelet-preserving solution (ThromboSol®) and 2% DMSO
5. Description of an in vitro platelet function analyzer-PFA100(TM)
6. Use of a novel platelet function analyzer (PFA-100(TM)) with high sensitivity to disturbances in von Willebrand factor to screen for von Willebrand's disease and other disorders
7. PFA-100(TM) system: A new method for assessment of platelet dysfunction
8. Use of the PFA-100® in the assessment of primary, platelet-related hemostasis in a pediatric setting
9. Evaluation of the hemostatic function of stored platelet concentrates using the platelet function analyser (PFA-100(TM))