Required structure of cationic peptide for oligonucleotide-binding and -delivering into cells

Journal of Peptide Science

Volumn 6, Issue 6, 2000, Pages 271-279

  Niidome, Takuro ^a   Wakamatsu, Masato ^a   Wada, Akihiro ^a   Hirayama, Toshiya ^a   Aoyagi, Haruhiko ^a  

^a NAGASAKI UNIVERSITY   (Japan)

Author keywords

Cationic peptide; Cell; Delivery; Oligonucleotide; helical peptide

Indexed keywords

AMPHOPHILE; ANTISENSE OLIGONUCLEOTIDE; CATION; OLIGONUCLEOTIDE; PEPTIDE;

ANIMAL CELL; ARTICLE; CELL TRANSFER; CONTROLLED STUDY; CYTOTOXICITY; HYDROPHOBICITY; KIDNEY CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN STRUCTURE;

EID: 0033829263     PISSN: 10752617     EISSN: None     Source Type: Journal    
DOI: 10.1002/1099-1387(200006)6:6<271::AID-PSC249>3.3.CO;2-6     Document Type: Article

References (22)

1. Antisense oligonucleotides: A new therapeutic principle
2. Antisense oligonucleotides as therapeutic agents - Is the bullet really magical?
3. Strategies for targeted gene therapy
4. Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure
5. A serum-resistant cytofectin for cellular delivery of antisense oligodeoxynucleotides and plasmid DNA
6. Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA
7. Strategies to achieve targeted gene delivery via the receptor-mediated endocytosis pathway
8. Sequence-specific inhibition of human immunodeficiency virus (HIV) reverse transcription by antisense oligonucleotides: Comparative study in cell-free assays and in HIV-infected cells
9. Dendrimer delivery of oligonucleotides
10. Electroporation: Application to human lymphoid cell lines for stable introduction of a transactivator gene of human T-cell leukemia virus type I
11. A new peptide vector for efficient delivery of oligonucleotides into mammalian cells
12. Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers
13. Binding of cationic α-helical peptides to plasmid DNA and their gene transfer abilities into cells
14. Importance of hydrophobic region in amphiphilic structures of α-helical peptides for their gene transfer-ability into cells
15. Specific inhibition of hepatitis C virus expression by antisense oligodeoxynucleotides in vitro model for selection of target sequence
16. Detection of undegraded oligonucleotides in vivo by fluorescence resonance energy transfer, nuclease activities in living sea urchin eggs
17. Interaction of α-helical peptides with phospholipid membrane: Effects of chain length and hydrophobicity of peptides
18. Design and synthesis of amphiphilic α-helical model peptides with systematically varied hydrophobic-hydrophilic balance and their interaction with lipid- and bio-membranes
19. Condensation of DNA and chromatin by SPKK-containing octapeptide repeat motif present in the C-terminus of histon H1
20. Purification, composition, and activity of two bactenecins, antibacterial peptides of bovine neutrophils
21. Functional domain and poly-L-proline II conformation for candidacidal activity of bactenecin 5
22. Structure and property of model peptides of proline/arginine-rich region in bactenecin 5