Impaired response to hepatocyte growth factor in FRTL-5 rat thyroid cells expressing a functional hepatocyte growth factor receptor

Thyroid

Volumn 10, Issue 8, 2000, Pages 631-640

  Bergstrom, J D ^a   Nilsson, M ^b   Heldin, N E ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; MESSENGER RNA; MONOCLONAL ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN C FOS; PROTEIN P85; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; THYROTROPIN; VINCULIN;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL DIFFERENTIATION; CELL GROWTH; CELL LINE; CELL PROLIFERATION; CELL SHAPE; CELL STIMULATION; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; THYROID CELL;

EID: 0033825508     PISSN: 10507256     EISSN: None     Source Type: Journal    
DOI: 10.1089/10507250050137699     Document Type: Article

References (46)

1. The biology of Hepatocyte growth factor/Scatter factor
2. Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product
3. Tyrosines 1234-1235 are critical for activation of the tyrosine kinase encoded by the Met proto-oncogene (HGF receptor)
4. A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family
5. Autophosphorylation promotes complex formation of recombinant hepatocyte growth factor receptor with cytoplasmic effectors containing SH2 domains
6. Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis
7. The receptor encoded by the human c-MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors
8. Overexpression of the c-MET/HGF receptor gene in human thyroid carcinomas
9. Mitogenic, dedifferentiating, and scattering effects of hepatocyte growth factor on dog thyroid cells
10. Mitogenic stimulation of normal and oncogene-transformed human thyroid epithelial cells by hepatocyte growth factor
11. Tissue distribution of hepatopoietin-A: A heparin-binding polypeptide growth factor for hepatocytes
12. Culture of hormone-dependent functional epithelial cells from rat thyroids
13. 125I]iodine uptake in FRTL-5 rat thyroid cells
14. Epidermal growth factor, but not thyrotropin, stimulates the expression of c-fos and c-myc messenger ribonucleic acid in porcine thyroid follicle cells in primary culture
15. Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA
16. Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor
17. Chromosomal localization of rat hepatocyte growth factor (Hgf) and HGF receptor (Met) and characterization of HGF receptor cDNA
18. Structure of the FBJ murine osteosarcoma virus genome: Molecular cloning of its associated helper virus and the cellular homolog of the v-fos gene from mouse and human cells
19. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrongenase cDNAs: Genomic complexity and molecular evolution of the gene
20. Iodide transport in primary cultured thyroid follicle cells: Evidence of a TSH-regulated channel mediating iodide efflux selectively across the apical domain of the plasma membrane
21. Growth stimulation of rat fetal hepatocytes in response to hepatocyte growth factor: Modulation of c-myc and c-fos expression
22. Transforming growth factor-beta promotes epidermal growth factor-induced thyroid cell migration and follicle neoformation in collagen gel separable from cell proliferation
23. Epidermal growth factor controls the proliferation and the expression of differentiation in canine thyroid cells in primary culture
24. Growth factors, thyroid hyperplasia and neoplasia
25. The cyclic AMP-mediated stimulation of cell proliferation
26. Stimulation by thyrotropin and cyclic AMP of the proliferation of quiescent canine thyroid cells cultured in a defined medium containing insulin
27. Control of human thyroid follicular cell proliferation in suspension and monolayer culture
28. Thyrotropin is not a growth factor for human thyroid cells in culture
29. The effects of growth factors and serum on DNA synthesis and differentiation in thyroid cells in culture
30. Immediate early gene expression in dog thyrocytes in response to growth, proliferation, and differentiation stimuli
31. Thyrotrophin stimulation of mitogenesis of the rat thyroid cell strain FRTL-5: A metaphase index assay for the detection of thyroid growth stimulators
32. Growth and differentiation in cultured human thyroid cells: Effects of epidermal growth factor and thyrotropin
33. Epidermal growth factor modulates thyroid growth and function in culture
34. Characterization of epidermal growth factor receptor in a rat thyroid cell line, FRTL-5
35. Transforming growth factor-beta induces cytoskeleton and extracellular matrix modifications in FRTL-5 thyroid epithelial cells
36. Growth factor-dependent activation of alphavbeta3 integrin in normal epithelial cells: Implications for tumor invasion
37. The p16(INK4a) tumour suppressor protein inhibits alphavbeta3 integrin-mediated cell spreading on vitronectin by blocking PKC-dependent localization of alphavbeta3 to focal contacts
38. Identification of protein kinase C and its multiple isoforms in FRTL-5 thyroid cells
39. Antagonistic effects of thyrotropin and epidermal growth factor on thyroglobulin mRNA level in cultured thyroid cells
40. Multiple mechanisms of interference between transformation and differentiation in thyroid cells
41. Ha-ras interference with thyroid cell differentiation is associated with a down-regulation of thyroid transcription factor-1 phosphorylation
42. Dissociation between transformed and differentiated phenotype in rat thyroid epithelial cells after transformation with a temperature-sensitive mutant of the Kirsten murine sarcoma virus
43. Activated ras and net oncogenes induce over-expression of c-met (hepatocyte growth factor receptor) in human thyroid epithelial cells
44. Mutated human Kirsten ras, driven by a thyroglobulin promoter, induces a growth advantage and partially dedifferentiates rat thyroid epithelial cells in vitro
45. Newly synthesized Rho A, not Ras, is isoprenylated and translocated to membranes coincident with progression of the G1 to S phase of growth-stimulated rat FRTL-5 cells
46. Basic fibroblast growth factor affects DNA synthesis and cell function and activates multiple signalling pathways in rat thyroid FRTL-5 and pituitary GH3 cells