Carbopeptides: Chemoselective ligation of peptide aldehydes to an aminooxy-functionalized D-galactose template

Journal of Peptide Science

Volumn 6, Issue 6, 2000, Pages 290-299

  Brask, Jesper ^a   Jensen, Knud J ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

C terminal peptide aldehyde; Carbohydrate; Carbopeptide; Chemoselective oxime ligation; De novo design; Template assembled synthetic protein

Indexed keywords

ALDEHYDE DERIVATIVE; AMINOOXYACETIC ACID; CARBOHYDRATE; CARBOPEPTIDE; CHIMERIC PROTEIN; CYCLOPEPTIDE; GALACTOSE; PEPTIDE; PYRANOSIDE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; LIGATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

ALDEHYDES; CARBON; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GALACTOSE; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; OXIMES; PEPTIDE BIOSYNTHESIS; PEPTIDES;

EID: 0033825139     PISSN: 10752617     EISSN: None     Source Type: Journal    
DOI: 10.1002/1099-1387(200006)6:6<290::AID-PSC257>3.0.CO;2-L     Document Type: Article

References (29)

1. Protein design, a minimalist approach
2. Native-like and structually characterized designed α-helical bundles
3. Controlling topology and native-like behavior of de novo-designed peptides: Design and characterization of antiparallel four-stranded coiled coils
4. De-novo protein design - From molten globules to native-like states
5. The construction of new proteins. Part III. Artificial folding units by assembly of amphiphilic secondary structures on a template
6. Template-assembled synthetic proteins with four-helix-bundle topology. Total chemical synthesis and conformational studies
7. A convenient synthesis of cyclic peptides as regioselectively addressable functionalized templates (RAFT)
8. Helichrome: Synthesis and enzymatic activity of a designed hemeprotein
9. Tetraphilin: A four-helix proton channel built on a tetraphenylporphyrin framework
10. Cavitand templated de novo four-helix bundles poster # 356
11. Facile synthesis of homogeneous artificial proteins
12. Storungstheoretische behandlung der chemischen reaktivitat
13. Unprotected peptides as building blocks for the synthesis of peptide dendrimers with oxime, hydrazone, and thiazolidine linkages
14. Synthesis of proteins by native chemical ligation
15. Extending the applicability of native chemical ligation
16. Chemical ligation approach to form a peptide bond between unprotected peptide segments. Concept and model study
17. Convenient total synthesis of a 4-helix TASP molecule by chemoselective ligation
18. Design, synthesis, and properties of a novel cytochrome b model
19. Modular synthesis of de novo-designed metalloproteins for light-induced electron transfer
20. Synthesis of antiparallel 4α-helix bundle TASP by chemoselective ligation
21. Nonpeptidal peptidomimetics with a β-D-glucose scaffolding. A partial somatostatin agonist bearing a close structural relationship to a potent, selective substance P antagonist
22. De novo design and synthesis of somatostatin non-peptide peptidomimetics utilizing β-D-glucose as a novel scaffolding
23. Carbohydrates as templates for de novo design of proteins
24. Principles and practice of solid-phase peptide synthesis
25. Backbone amide linker (BAL) strategy for solid-phase synthesis of C-terminal-modified and cyclic peptides
26. Preparation and properties of N(α)-di-tert-butoxycarbonyl amino acids. Applicability in the synthesis of Leu-enkephalin
27. Template assembled synthetic proteins: Condensation of a multifunctional peptide to a topological template via chemoselective ligation
28. Total chemical synthesis of a unique transcription factor-related protein: cMyc-Max
29. Monosaccharides