The expression of Myf5 in the developing mouse embryo is controlled by discrete and dispersed enhancers specific for particular populations of skeletal muscle precursors

Development

Volumn 127, Issue 17, 2000, Pages 3745-3757

  Summerbell, D ^a   Ashby, P R ^a   Coutelle, O ^a   Cox, D ^a   Yee, S P ^a   Rigby, P W J ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Branchial arch; Epaxial; Hypaxial; MRF; Muscle; Myf5; Myogenic regulatory factor

Indexed keywords

MYOD PROTEIN; MYOGENIC FACTOR 5; MYOGENIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL FATE; CELL MIGRATION; CELL POPULATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENHANCER REGION; FACE MUSCLE; GENE EXPRESSION REGULATION; GENE LOCUS; GENETIC TRANSCRIPTION; LIMB BUD; MOUSE; MUSCLE DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; REGULATOR GENE; REGULATORY MECHANISM; REPORTER GENE; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; STEM CELL; TRANSGENE; VERTEBRATE;

ANIMALIA; MAMMALIA; VERTEBRATA;

EID: 0033825079     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.127.17.3745     Document Type: Article

References (69)

1. The regulation of MyoD gene expression: Conserved elements mediate expression in embryonic axial muscle
2. Sonic hedgehog controls epaxial muscle determination through Myf5 activation
3. Inactivation of Myf-6 and Myf-5 genes in mice leads to alterations in skeletal muscle development
4. MyoD expression marks the onset of skeletal myogenesis in Myf-5 mutant mice
5. Myf-6, a new member of the human gene family of myogenic determination factors: Evidence for a gene cluster on chromosome 12
6. A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts
7. Myogenic specification in somites: Induction by axial structures
8. Separable regulatory elements governing myogenin transcription in mouse embryogenesis
9. On the role of connective tissue in the patterning of the chick limb musculature
10. Limb-somite relationship: Origin of the limb musculature
11. Early stages of chick somite development
12. Local signalling in dermomyotomal cell type specification
13. Experimental analysis of the origin of the wing musculature in avian embryos
14. Activation of different myogenic pathways: Myf-5 is induced by the neural tube and MyoD by the dorsal ectoderm in mouse paraxial mesoderm
15. How is myogenesis initiated in the embryo?
16. Expression of a single transfected cDNA converts fibroblasts to myoblasts
17. Specification of the hypaxial musculature
18. A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program
19. Patterning of mammalian somites by surface ectoderm and notochord: Evidence for sclerotome induction by a hedgehog homolog
20. A modular set of lacZ fusion vectors for studying gene expression in Caenorhabditis elegans
21. Two domains of MyoD mediate transcriptional activation of genes in repressive chromatin: A mechanism for lineage determination in myogenesis
22. Embryonic activation of the myoD gene is regulated by a highly conserved distal control element
23. Regulatory elements that control the lineage-specific expression of myoD
24. A distinct developmental programme for the cranial paraxial mesoderm in the chick embryo
25. Wnt signaling from the dorsal neural tube is required for the formation of the medial dermo-myotome
26. MyoD and Myf5 differentially regulate the development of limb versus trunk skeletal muscle
27. Rhombencephalic neural crest segmentation is preserved throughout craniofacial ontogeny
28. Fine-scale transgenic mapping of the MyoD core enhancer: MyoD is regulated by distinct but overlapping mechanisms in myotomal and non-myotomal muscle lineages
29. Autoproteolysis in hedgehog protein biogenesis
30. Migration of hypoglossal myoblast precursors
31. Mox2 is a component of the genetic hierarchy controlling limb muscle development
32. Distribution of Sonic hedgehog peptides in the developing chick and mouse embryo
33. MyoD is required for myogenic stem cell function in adult skeletal muscle
34. Herculin, a fourth member of the MyoD family of myogenic regulatory genes
35. Combinatorial signals from the neural tube, floor plate and notochord induce myogenic bHLH gene expression in the somite
36. Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite
37. The embryonic origins of avian cephalic and cervical muscles and associated connective tissues
38. Patterning of avian craniofacial muscles
39. Know your neighbors: Three phenotypes in null mutants of the myogenic bHLH gene MRF4
40. Knowing chops from chuck: Roasting myoD redundancy
41. Early expression of the myogenic regulatory gene, myf-5, in precursor cells of skeletal muscle in the mouse embryo
42. Isolated sequences from the linked Myf-5 and MRF4 genes drive distinct patterns of muscle-specific expression in transgenic mice
43. Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome
44. Control of somite patterning by signals from the lateral plate
45. Control of dorso-ventral patterning of somitic derivatives by notochord and floor plate
46. Lateral and axial signals involved in avian somite patterning: A role for BMP4
47. Overlapping functions of the myogenic bHLH genes MRF4 and MyoD revealed in double mutant mice
48. Identification of MRF4: A new member of the muscle regulatory factor gene family
49. Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis
50. The neural tube/notochord complex is necessary for vertebral but not limb and body wall striated muscle differentiation
51. MyoD or Myf-5 is required for the formation of skeletal muscle
52. Molecular Cloning: A Laboratory
53. Expression of two myogenic regulatory factors myogenin and MyoD1 during mouse embryogenesis
54. Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site
55. Neural tube and notochord promote in vitro myogenesis in single somite explants
56. Mouse limb muscle is determined in the absence of the earliest myogenic factor myf-5
57. Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD
58. A population of myogenic cells derived from the mouse neural tube
59. A novel myoblast enhancer element mediates MyoD transcription
60. Consequences of neural tube and notochord excision on the development of the peripheral nervous system in the chick embryo
61. Cranial paraxial mesoderm and neural crest cells of the mouse embryo: Co-distribution in the craniofacial mesenchyme but distinct segregation in branchial arches
62. Myogenin is required for late but not early aspects of myogenesis during mouse development
63. Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD
64. Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression
65. Whole mount in situ hybridization of vertebrate embryos
66. Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD
67. The regulation of myogenin gene expression during the embryonic development of the mouse
68. Inactivation of the myogenic bHLH gene MRF4 results in up-regulation of myogenin and rib anomalies
69. Faithful expression of the Myf-5 gene during mouse myogenesis requires distant control regions: A transgene approach using yeast artificial chromosomes