Dissociation of DNA double strand by hypohalous acids

Redox Report

Volumn 5, Issue 4, 2000, Pages 243-247

  Shishido, N ^a   Nakamura, S ^b   Nakamura, M ^a  

^a ASAHIKAWA MEDICAL COLLEGE   (Japan)

^b HIROSAKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 CHLORO 5,5 DIMETHYL 1,3 CYCLOHEXANEDIONE; ANTIOXIDANT; ASCORBIC ACID; CHLORIDE PEROXIDASE; CHLORINE; DOUBLE STRANDED DNA; ETHIDIUM BROMIDE; GLUTATHIONE; HYDROGEN PEROXIDE; HYPOCHLOROUS ACID; INORGANIC ACID; KETONE DERIVATIVE; MYELOPEROXIDASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CATTLE; CHLORINATION; COMPLEX FORMATION; CONTROLLED STUDY; DISSOCIATION; DNA DAMAGE; FLUORESCENCE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; STOICHIOMETRY; THYMUS;

ANIMALIA; BOS TAURUS;

EID: 0033824944     PISSN: 13510002     EISSN: None     Source Type: Journal    
DOI: 10.1179/135100000101535690     Document Type: Article

References (19)

1. Myeloperoxidase: Occurrence and biological function
2. Inside the neutrophil phagosome: Oxidants, myeloperoxidase, and bacterial killing
3. Nucleotide chloramines and neutrophil-mediated cytotoxicity
4. Biological reactivity of hypochlorous acid: Implications for microbicidal mechanisms of leukocyte myeloperoxidase
5. Vanadium peroxidases
6. Quantitating direct chlorine transfer from enzyme to substrate in chloroperoxidase-catalyzed reactions
7. Thyroid peroxidase: Experimental and clinical integration
8. Iodothyronine-induced catalytic activity of thyroid peroxidase
9. Oxidation of bromide by the human leukocyte enzymes myeloperoxidase and eosinophil peroxidase. Formation of bromamines
10. Hypochlorite-induced oxidation of proteins in plasma: Formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation
11. Chlorination of tyrosyl residues in peptides by myeloperoxidase and human neutrophils
12. Degradation of hyaluronic acid, poly- and monosaccharides, and model compounds by hypochlorite: Evidence for radical intermediates and fragmentation
13. Hypochlorous acid interactions with thiols, nucleotides, DNA, and other biological substrates
14. Interactions of hypochlorous acid with pyrimidine nucleotides, and secondary reactions of chlorinated pyrimidines with GSH, NADH, and other substrates
15. The mechanism of myeloperoxidase dependent chlorination of monochlorodimedone
16. Kinetics and mechanisms of hypochlorous acid reactions
17. A fluorescence complex between ethidium bromide and nucleic acids. Physical-chemical characterization
18. Comparative reactivities of various biological compounds with myeloperoxidase-hydrogen peroxide-chloride, and similarity of the oxidant to hypochlorite
19. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils