Comparative study of lymphocyte-suppressive potency between prednisolone and methylprednisolone in rheumatoid arthritis

Immunopharmacology

Volumn 49, Issue 3, 2000, Pages 411-417

  Hirano, Toshihiko ^a   Tsuboi, Norioki ^b   Homma, Masato ^a   Oka, Kitaro ^a   Takekoshi, Tohru ^b   Tahara, Koichiro ^b   Takanashi, Hirofumi ^b   Abe, Haruo ^b   Urata, Yukitomo ^b   Hayashi, Tohru ^b  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Lymphocyte suppressive potency; Lymphocyte blastogenesis; Methylprednisolone; Prednisolone; Rheumatoid arthritis

Indexed keywords

METHYLPREDNISOLONE; PREDNISOLONE; RHEUMATOID FACTOR;

ADULT; AGED; ARTICLE; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; DRUG SENSITIVITY; FEMALE; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; KIDNEY TRANSPLANTATION; LYMPHOCYTE TRANSFORMATION; MALE; MONONUCLEAR CELL; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; T LYMPHOCYTE;

EID: 0033824879     PISSN: 01623109     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-3109(00)00263-0     Document Type: Article

References (26)

1. B.S. Bochner B.K. Rutledge R.P. Schleimer Interleukin 1 production by human lung tissue: II. Inhibition by anti-inflammatory steroids J. Immunol. 139 1987 2303 2307
2. A.C. Braude A.S. Rebuck Prednisolone and methylprednisolone disposition in the lung Lancet ii 1983 995
3. D.A. Carson P.P. Chen T.J. Kipps New roles for rheumatoid factor J. Clin. Invest. 87 1991 379 383
4. C.J. Corrigan P.H. Brownm N.C. Barnes S.J. Szefler J.-J. Tsai A.J. Frew A.B. Kay Glucocorticoid resistance in chronic asthma; glucocorticoid pharmacokinetics, glucocorticoid receptor characteristics, and inhibition of peripheral blood T cell proliferation by glucocorticoids in vitro Am. Rev. Respir. Dis. 144 1991 1016 1025
5. C.J. Corrigan P.H. Brown N.C. Barnes J.-J. Tsai A.J. Frew A.B. Kay Glucocorticoid resistance in chronic asthma; peripheral blood T lymphocyte activation and comparison of the T lymphocyte inhibitory effects of glucocorticoids and cyclosporine A Am. Rev. Respir. Dis. 144 1991 1026 1032
6. H. Derendorf G. Hochhaus H. Mollmann J. Barth M. Krieg S. Tunn C. Mollman Receptor-based pharmacokinetic–pharmacodynamic analysis of corticosteroids J. Clin. Pharmacol. 33 1993 115 123
7. C.A. Dinarello J.W. Mier Lymphokines N. Engl. J. Med. 317 1987 940 945
8. L.J. Dumble I.M. Macdonald P. Kincaid-Smith G.J.A. Clunie Correlation between ADCC resistance to in vitro steroid and renal allograft failure Transplant. Proc. 13 1981 1569 1571
9. L.S. Greos P. Vichyanond D.C. Bloedow C.G. Irvin G.L. Larsen S.J. Szefler M.R. Hill Methylprednisolone achieves greater concentrations in the lung than prednisolone Am. Rev. Respir. Dis. 144 1991 586 592
10. K.A. Haycock R. Roth J. Gagnon Statview 1994 Calif. Abacus Concepts Berkeley
11. T. Hirano K. Oka E. Kawashima M. Akiba Effects of synthetic and naturally occurring flavonoids on mitogen-induced proliferation of human peripheral-blood lymphocytes Life Sci. 45 1989 1407 1411
12. T. Hirano K. Oka E. Sakurai T. Tamaki M. Kozaki Impaired prednisolone sensitivities of endocrine system as well as that of peripheral-blood lymphocytes are closely related to clinical incidence in renal transplantation J. Pharm. Pharmacol. 43 1991 569 573
13. T. Hirano K. Oka H. Takeuchi E. Sakurai N. Matsuno T. Tamaki M. Kozaki Clinical significance of glucocorticoid pharmacodynamics assessed by antilymphocyte action in kidney transplantation; marked difference between prednisolone and methylprednisolone Transplantation 57 1994 1342 1348
14. T. Hirano K. Oka T. Tamaki Gramicidin as a potential immunosuppressant for organ transplantation J. Pharmacol. Exp. Ther. 273 1995 223 229
15. T. Hirano K. Oka H. Takeuchi K. Kozaki N. Matsuno T. Nagao M. Kozaki M. Ichikawa M. Yoshida Y. Umezawa M. Hirata T. Oh-i M. Koga Immunosuppressant pharmacodynamics on lymphocytes from healthy subjects and patients with chronic renal failure, nephrosis, and psoriasis: possible implication for individual therapeutic efficacy Clin. Pharmacol. Ther. 62 1997 652 664
16. T. Hirano K. Oka Y. Umezawa M. Hirata T. Oh-i M. Koga Individual pharmacodynamics assessed by antilymphocyte action predicts clinical cyclosporine efficacy in psoriasis Clin. Pharmacol. Ther. 63 1998 465 470
17. X.X. Kang T. Hirano K. Oka E. Sakurai T. Tamaki M. Kozaki Altered prednisolone-specific lymphocyte sensitivity in chronic renal failure may play a role of pharmacodynamic marker of acute allograft rejection following kidney transplantation Eur. J. Clin. Pharmacol. 41 1991 417 423
18. B.W. Kirkman M.M. Corkill S.C. Daviso G.S. Panayi Response to glucocorticoid treatment in rheumatoid arthritis: in vitro cell mediated immune assay predicts in vivo responses J. Rheumatol. 18 1991 821 825
19. R. Kirnbauer A. Kock P. Neuner E. Foster J. Krutmann A. Urbanski E. Schauer J.C. Ansel T. Schwarz T.A. Luger Regulation of epidermal cell interleukin-6 production by UV light and corticosteroids J. Invest. Dermatol. 96 1991 484 489
20. E. Langhoff J. Ladefoged Relative immunosuppressive potency of various corticosteroids measured in vitro Eur. J. Clin. Pharmacol. 25 1983 459 462
21. E. Langhoff J. Ladefoged B.K. Jakobsen P. Platz L.P. Ryder A. Svejgaard J.H. Thaysen Recipient lymphocyte sensitivity to methylprednisolone affects cadaver kidney graft survival Lancet ii 1986 1296 1297
22. D.M. Malchoff A. Brufsky G. Reardon P. McDermott E.C. Javier C.H. Bergh D. Rowe C.D. Malchoff A mutation of the glucocorticoid receptor in primary cortisol resistance J. Clin. Invest. 91 1993 1918 1925
23. V. Pakit G.I. Charles L.L. Gary J.S. Stanley R.H. Malcolm Penetration of corticosteroids into the lung: evidence for a difference between methylprednisolone and prednisolone J. Allergy Clin. Immunol. 84 1989 867 873
24. J.M. Sargent C.G. Taylor Appraisal of the MTT assay as a rapid test of chemosensitivity in acute myeloid leukaemia Br. J. Cancer 60 1989 206 210
25. S.J. Szefler Measuring the response to glucocorticoids J. Allergy Clin. Immunol. 85 1990 985 987
26. U.G. Wagner K. Koetz C.M. Weyand J.J. Goronzy Perturbation of the T cell repertoire in RA Proc. Natl. Acad. Sci. 95 1998 14447 14452