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Volumn 26, Issue 3, 2000, Pages 177-185

Gamma heavy chain disease in man: Independent structural abnormalities and reduced transcription of a functionally rearranged lambda L-chain gene result in the absence of L-chains

Author keywords

Heavy chain disease; Immunoglobulins; Light chains; Mutations; Transcription

Indexed keywords

IMMUNOGLOBULIN LIGHT CHAIN; MESSENGER RNA; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR;

EID: 0033822703     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1006/bcmd.2000.0294     Document Type: Article
Times cited : (4)

References (40)
  • 6
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • (1975) Nature , vol.256 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 8
    • 0016700864 scopus 로고
    • Detection of specific sequences among DNA fragments separated by gel electrophoresis
    • (1975) J. Mol. Biol. , vol.98 , pp. 503-517
    • Southern, E.M.1
  • 10
    • 0020971298 scopus 로고
    • Exonuclease III: Use for DNA sequence analysis and in specific deletions of nucleotides
    • (1983) Methods Enzymol. , vol.100 , pp. 60-96
    • Guo, L.H.1    Wu, R.2
  • 12
    • 0002471282 scopus 로고
    • Dideoxynucleotide sequencing of RNA and uncloned cDNA
    • (1987) Focus , vol.9 , pp. 5-7
    • Geliebter, J.1
  • 13
    • 0001190006 scopus 로고
    • Identification of newly transcribed RNA
    • Current Protocols in Molecular Biology Section (Ausubel, F. M., Brent, R., Kingston, R. E., et al., Eds.), Greene Publishing and Wiley Interscience, New York
    • (1987) , pp. 410
    • Greenberg, M.E.1
  • 24
    • 0025026388 scopus 로고
    • Gene deletions force nonsecretory alpha-chain disease plasma cells to produce membrane-form alpha-chain only
    • (1990) J. Immunol. , vol.145 , pp. 2455-2458
    • Cogne, M.1    Preud'homme, J.2
  • 27
    • 0016311149 scopus 로고
    • Synthesis of a carboxyterminal constant region fragment of the immunoglobulin light chain by a mouse myeloma cell line
    • (1974) J. Mol. Biol. , vol.89 , pp. 409-421
    • Kuehl, W.M.1    Scharff, M.D.2
  • 28
    • 0017659190 scopus 로고
    • Cloned MPC11 myeloma cells express two kappa genes: A gene for a complete light chain and a gene for a constant region polypeptide
    • (1977) Cell , vol.12 , pp. 453-462
    • Rose, S.M.1    Kuehl, W.M.2    Smith, G.P.3
  • 30
    • 0019330405 scopus 로고
    • A mutant immunoglobulin light chain is formed by aberrant DNA and RNA-splicing events
    • (1980) Nature , vol.286 , pp. 779-783
    • Seidman, J.G.1    Leder, P.2
  • 31
    • 0022930702 scopus 로고
    • Inducibility of κ immunoglobulin enhancer-binding protein NF-kB by a posttranslational mechanism
    • (1986) Cell , vol.47 , pp. 921-928
    • Sen, R.1    Baltimore, D.2
  • 39
  • 40
    • 0025007007 scopus 로고
    • Immunoglobulin heavy chain binding protein complexes are dissociated in vivo by light chain addition
    • (1990) J. Cell Biol. , vol.111 , pp. 829-837
    • Hendershot, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.