An integrin chicken and egg problem: Which comes first, the extracellular matrix or the cytoskeleton?

Current Opinion in Cell Biology

Volumn 12, Issue 5, 2000, Pages 629-633

  Brown, Nicholas H ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN;

CAENORHABDITIS ELEGANS; CELL ADHESION; CELL DIFFERENTIATION; CELL MIGRATION; CYTOSKELETON; DROSOPHILA; EMBRYO DEVELOPMENT; EXTRACELLULAR MATRIX; MUSCLE CONTRACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; REVIEW; SARCOMERE;

EID: 0033822476     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-0674(00)00142-3     Document Type: Review

References (36)

1. Integrins as mediators of morphogenesis in Drosophila
2. Cell adhesion via the ECM: Integrin genetics in fly and worm
3. The mesoderm and its derivatives
4. Muscle: Structure, function and development
5. Genome sequence of the nematode C. elegans: A platform for investigating biology
6. Genes critical for muscle development and function in Caenorhabditis elegans identified through lethal mutations
7. Neuronal migrations and axon fasciculation are disrupted in ina-1 integrin mutants
8. The genome sequence of Drosophila melanogaster
9. The function of PS integrins during Drosophila embryogenesis
10. PS2 integrin requirements in Drosophila embryo and wing morphogenesis
11. Null mutations in the αPS2 and βPS2 integrin subunit genes have distinct phenotypes
12. In Drosophila embryos, the absence of the PS integrins or laminin A affects the extraceliular adhesion of hemiadherens and neuromuscular junctions, but not their intracellular assembly
13. A novel α integrin subunit associates with βPS and functions in tissue morphogenesis and movement during Drosophila development
14. A novel, tissue-specific integrin subunit, βγ expressed in the midgut of Drosophila melanogaster
15. Characterization of βpat-3 heterodimers, a family of essential integrin receptors in C. elegans
16. Mutations and expressions of the tropomyosin gene and the troponin C gene of Caenorhabditis elegans
17. A role for integrin in the formation of sarcomeric cytoarchitecture
18. Genetic analysis of the Drosophila α(PS2) integrin subunit reveals discrete adhesive, morphogeneti and sarcomeric functions
19. Vinculin is essential for muscle function in the nematode
20. Assembly of body wall muscle cell attachment structures in Caenorhabditis elegans
21. Products of the unc-52 gene in Caenorhabditis elegans are homologous to the core protein of the mammalian basement membrane heparin sulfate proteoglycan
22. Talin requires β-integrin, but not vinculin, for its assembly into focal adhesion-like structures in the nematode Caenorhabditis elegans
23. A conserved LIM portein that affects muscular adherens junction integrity and mechanosensory function in Caenorhabditis elegans
24. Tiggrin, a novel Drosophila extracellular matrix protein that functions as a ligand for Drosophila α(PS2)β(PS) integrins
25. The PS2 integrin ligand tiggrin is required for proper muscle function in Drosophila
26. Dcg1 α-iv collagen chain of Drosophila melanogaster is synthesized during embryonic organogenesis by mesenchymal cells and is deposited in muscle basement membranes
27. Wing blister, a new Drosophila laminin alpha chain required for cell adhesion and migration during embryonic and imaginal development
28. Type IV collagen is detectable in most, but not all, basement membranes of Caenorhabditis elegans and assembles on tissues that do not express it
29. Cell autonomous expression of perlecan and plasticity of cell shape in embryonic muscle of Caenorhabditis elegans
30. Intracellular signals direct integrin localization to sites of function in embryonic muscles
31. A histological and ultrastructural analysis of developmental defects produced by the mutation, lethal(1)myospheroid, in Drosophila melanogaster
32. Focal adhesion assembly
33. Autosomal mutations affecting adhesion between wing surfaces in Drosophila melanogaster
34. A screen to identify Drosophila genes required for integrin mediated adhesion
35. The UNC-112 gene in Caenorhabditis elegans encodes a novel component of cell-matrix adhesion structures required for integrin localization in the muscle cell membrane
36. The localized assembly of extracellular matrix integrin ligands requires cell-cell contact