Rapid gas chromatographic procedure for the determination of topiramate in serum

Journal of Analytical Toxicology

Volumn 24, Issue 7, 2000, Pages 661-663

  Wolf, Carl E ^a   Crooks, C Richard ^a   Poklis, Alphonse ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; BACLOFEN; CARBAMAZEPINE; CHOLESTEROL; CYCLOSPORIN; DISOPYRAMIDE; ETHOSUXIMIDE; GENTAMICIN; LIDOCAINE; MEPIVACAINE; METHOTREXATE; NETILMICIN; NITROGEN; PARACETAMOL; PHENOBARBITAL; PRIMIDONE; QUINIDINE; THEOPHYLLINE; TOBRAMYCIN; TOPIRAMATE; TRIACYLGLYCEROL; UREA; VALPROIC ACID;

ACCURACY; ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CROSS REACTIVITY; DRUG DETERMINATION; EXTRACTION AND EXTRACTS; GAS CHROMATOGRAPHY; HUMAN; SEIZURE; SERUM; STANDARD; VALIDATION PROCESS;

ANTICONVULSANTS; CHROMATOGRAPHY, GAS; FRUCTOSE; HUMAN; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 0033819818     PISSN: 01464760     EISSN: None     Source Type: Journal    
DOI: 10.1093/jat/24.7.661     Document Type: Article

References (8)

1. Antiepileptic drugs: Pharmacological mechanisms and clinical efficacy with consideration of promising development stage compounds
2. Plasma pharmacokinetics of topiramate, a new anticonvulsant in humans
3. Drug interaction profile of topiramate
4. Therapeutic monitoring of the new antiepileptic drugs
5. Automated capillary gas chromatographic assay using flame ionization detection for the determination of topiramate in plasma
6. A capillary gas chromatographic assay with nitrogen phosphorus detection for the quantification of topiramate in human plasma, urine and whole blood
7. In vivo microdialysis and liquid chromatography/thermospray mass spectrometry of the novel anticonvulsant 2,3,4,5-bis-O-(1 methylethylidine)-beta-D-fructopyranose sulfamate (topiramate) in rat brain fluid
8. Distribution of topiramate in a medical examiner's case