Changes in mRNA expression levels of synaptic- and target tissue-specific proteins after organophosphate exposure

Legal Medicine

Volumn 2, Issue 2, 2000, Pages 55-63

  Matsuda, Hirokazu ^a   Seo, Yasuhisa ^a   Kakizaki, Eiji ^a   Takahama, Keiichi ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Acetylcholinesterase; Enolase; mRNA regulation; Nicotinic acetylcholine receptor; Organophosphate; RT PCR

Indexed keywords

ACETYLCHOLINESTERASE; DISULFOTON; ENOLASE; MESSENGER RNA; NEURON SPECIFIC ENOLASE; NICOTINIC RECEPTOR; ORGANOPHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE; GENE EXPRESSION REGULATION; MALE; NEUROMUSCULAR SYNAPSE; NEUROTOXICOLOGY; NONHUMAN; RAT; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCIATIC NERVE; SOLEUS MUSCLE; TRANSCRIPTION REGULATION;

EID: 0033819396     PISSN: 13446223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1344-6223(00)80024-3     Document Type: Article

References (38)

1. Protective effect of pralidoxime on muscle fiber necrosis induced by organophosphate compounds
2. Studies on the correlation between blood cholinesterase inhibition and target tissue inhibition in pesticide-treated rats
3. Anticholinesterases induce multigenic transcriptional feedback response suppressing cholinergic neurotransmission
4. Acute stress facilitates long-lasting changes in cholinergic gene expression
5. Pyridostigmine brain penetration under stress enhances neuronal excitability and induces early immediate transcriptional response
6. Reversible necrosis at the end-plate region in striated muscles of the rat poisoned with cholinesterase inhibitors
7. Chronic inhibition of cholinesterase as a cause of myopathy
8. Pesticide induced muscle necrosis: Mechanisms and prevention
9. Histological and histochemical study of paraoxon myopathy in the rat
10. Variable involvement of rat skeletal muscle in paraoxon-induced necrotizing myopathy
11. Attenuation of soman-induced lesions of skeletal muscle by acetyl-cholinesterase reactivating and non-reactivating antidotes
12. Neuromuscular dysfunction induced by acetylcholinesterase inhibition
13. 1 mRNA expression
14. 3H]quinuclidinyl benzilate binding in the striatum of rats following chronic cholinesterase inhibition with di-isopropylfluorophosphate
15. 3H]quinuclidinyl benzilate binding to muscarinic receptors in disulfoton-tolerant mice
16. Differential alterations of cholinergic muscarinic receptors during chronic and acute tolerance to organophosphorus insecticides
17. Carbachol- and norepinephrine-stimulated phosphoinositide metabolism in rat brain: Effect of chronic cholinesterase inhibition
18. Differential expression of α- and β-enolase genes during rat heart development and hypertrophy
19. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
20. Cloning and expression of a rat acetylcholinesterase subunit: Generation of multiple molecular forms and complementarity with a Torpedo collagenic sub-unit
21. Primary structure and functional expression of the α-, β-, γ-, δ-, ε-subunits of the acetylcholine receptor from rat muscle
22. cDNA cloning and nucleotide sequence of rat muscle-specific enolase (ββ enolase)
23. Molecular cloning and the nucleotide sequence of cDNA for neuron-specific enolase messenger RNA of rat brain
24. A new and rapid colorimetric determination of acetylcholinesterase activity
25. Protein measurement with the Folin phenol reagent
26. Relationship between acetylcholinesterase inhibition and the development of a myopathy
27. Initial ultrastructural abnormalities at the end plate produced by a cholinesterase inhibitor
28. Neostigmine-induced alterations at the mammalian neuromuscular junction. I. Muscle contraction and electrophysiology
29. Neostigmine-induced alterations at the mammalian neuromuscular junction. II. Ultrastructure
30. Ultrastructural changes at the end-plate produced by an irreversible cholinesterase inhibitor
31. Neostigmine myopathy is a calcium ion-mediated myopathy initially affecting the motor end-plate
32. Ciliary neurotrophic factor: Regulation of acetylcholinesterase in skeletal muscle and distribution of messenger RNA encoding its receptor in synaptic versus extrasynaptic compartments
33. Neural regulation of acetylcholinesterase mRNAs at mammalian neuromuscular synapses
34. Pesticides
35. Adenylate cyclase-coupled beta-adrenergic receptors: Structure and mechanisms of activation and desensitization
36. Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model
37. 2 muscarinic receptors of rat heart have high affinity for organophosphorus anticholinesterases
38. Effects of organophosphates and nerve growth factor on muscarinic receptor binding number in rat pheochromocytoma PC12 cells