Appropriate use and misuse of blood concentration measurements to quantitate first-pass metabolism

Journal of Laboratory and Clinical Medicine

Volumn 136, Issue 4, 2000, Pages 275-280

  Levitt, Michael D ^a   Levitt, David G ^a  

^a VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0033819243     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1067/mlc.2000.109100     Document Type: Article

References (11)

1. The critical role of the rate of ethanol absorption in the interpretation of studies purporting to demonstrate gastric metabolism of ethanol
2. First-pass metabolism of ethanol: An important determinant of blood levels after alcohol consumption
3. 2-receptor antagonists
4. High blood alcohol levels in women. The role of decreased gastric alcohol dehydrogenase activity and first-pass metabolism
5. Ranitidine increases the bioavailability of postprandial ethanol by the reduction of FPM
6. Disposition and FPM of ethanol in humans: Is it gastric or hepatic and does it depend on gender?
7. Glycine prevents alcohol-induced liver injury by decreasing alcohol in the rat stomach
8. First-pass metabolism of ethanol is strikingly influenced by the speed of gastric emptying
9. Gastric origin of the first-pass metabolism of ethanol in humans: Effect of gastrectomy
10. FPM of ethanol is predominantly gastric
11. Use of a two-compartment model to assess the pharmacokinetics of human ethanol metabolism