Inhibitory effect of fluvastatin on aortic intimal thickening in normocholesterolemic rabbits

Chinese Medical Sciences Journal

Volumn 15, Issue 3, 2000, Pages 140-144

  Ping, Y ^a   Daicheng, Y ^a   Ligong, S ^a   Xinxin, D ^a   Yali, Z ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Apoptosis; HMG CoA reductase inhibitor; Smooth muscle cells

Indexed keywords

CHOLESTEROL; FLUINDOSTATIN; LIPID; MESSENGER RNA; PROTEIN P53;

ABDOMINAL AORTA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTERY INTIMA PROLIFERATION; ARTICLE; BLOOD VESSEL INJURY; CELL PROLIFERATION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; LIPID BLOOD LEVEL; NONHUMAN; ONCOGENE H RAS; PROTEIN EXPRESSION; PROTO ONCOGENE; RABBIT; SMOOTH MUSCLE FIBER; TUMOR SUPPRESSOR GENE;

ANIMALS; ANTICHOLESTEREMIC AGENTS; AORTA, ABDOMINAL; APOPTOSIS; BALLOON DILATATION; CELL DIVISION; FATTY ACIDS, MONOUNSATURATED; GENE EXPRESSION; GENES, P53; GENES, RAS; INDOLES; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; RABBITS; RANDOM ALLOCATION; RNA, MESSENGER; TUNICA INTIMA;

EID: 0033817540     PISSN: 10019294     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Relationship between mevalonate pathway and arterial myocyte proliferation: In vitro studies with inhibitors of HMG-Co A reductase
2. p53 gene detection and p53 mRNA overexpression in breast cancer
3. Oncogene involved in tumor regression: H-ras activation in the rabbit keratoacanthoma model
4. Proapoptotic effect of atorvastatin on stimulated rabbit smooth muscle cells
5. Apoptosis after stent implantation compared with balloon angioplasty in rabbits
6. Apoptosis participates in cellularity regulation during rat aortic intimal thickening
7. Acute cellular damage in medial smooth muscle cells following experimental coronary angioplasty in dog. Damage of cytoskeleton and apoptosis
8. Inhibition of cellular ras prevents smooth muscle cell proliferation after vascular injury in vivo
9. HMG-CoA reductase inhibitors: In vivo effects on carotid intimal thickening in normocholesteroremic rabbits
10. Inhibitory effect of fluvastatin at doses insufficient to lower serum lipids on the catheter-induced thickening of intima in rabbit femoral artery
11. Inhibition of isoprenoid biosynthesis and arterial smooth muscle cell proliferation
12. Effect of HMG-CoA reductase inhibition on PDGF- and angiotensin II -mediated signal transduction: Supression of c-Jun and c-Fos in human smooth muscle cells in vitro