Linkage disequilibrium mapping in populations of variable size using the decay of haplotype sharing and a stepwise-mutation model

Genetic Epidemiology

Volumn 19, Issue SUPPL. 1, 2000, Pages

  Zhang, Shuanglin ^a   Zhao, Hongyu ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Coalescent model; Linkage disequilibrium; Stepwise mutation model

Indexed keywords

CONFERENCE PAPER; EPILEPTOGENESIS; GENE LINKAGE DISEQUILIBRIUM; GENE LOCATION; GENE MAPPING; GENE MUTATION; GENETIC MODEL; HAPLOTYPE; HUMAN; MYOCLONUS EPILEPSY; POPULATION GENETICS; POPULATION STRUCTURE;

CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 21; COMPUTER SIMULATION; EPILEPSIES, MYOCLONIC; HAPLOTYPES; HUMAN; LINKAGE DISEQUILIBRIUM; MICROSATELLITE REPEATS; MODELS, GENETIC; MODELS, STATISTICAL; MUTATION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

GENETTA;

EID: 0033815541     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/1098-2272(2000)19:1+<::AID-GEPI15>3.0.CO;2-1     Document Type: Conference Paper

References (8)

1. Launching microsatellites: A review of mutation processes and methods of phylogenetic inference
2. Ancestral inference in population genetics
3. Computational methods for the coalescent
4. The coalescent
5. Assessment of linkage disequilibrium by the decay of haplotype sharing with application to fine-scale genetic mapping
6. The model of mutation appropriate to estimate the number of electrophoretically detectable allele in a genetic population
7. Linkage-disequilibrium mapping of disease genes by reconstruction of ancestral haplotypes in founder populations
8. Progressive myoclonus epilepsy EPMI locus maps to a 175-kb interval in distal 21q