Characterization, cloning and immunogenicity of antigens released by transforming cercariae of Schistosoma mansoni

Parasitology

Volumn 121, Issue 4, 2000, Pages 385-394

  Harrop, R ^a,b   Jennings, N ^a   Mountford, A P ^a   Coulson, P S ^a   Wilson, R A ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

^b OXFORD BIOMEDICA UK LTD   (United Kingdom)

Author keywords

High level expression; Immunolocalization; Released proteins; Schistosoma mansoni; Sequence analysis

Indexed keywords

CALCIUM BINDING PROTEIN; CYTOCHROME C OXIDASE; GAMMA INTERFERON; GLUTATHIONE TRANSFERASE; LEUKOCYTE ELASTASE INHIBITOR; PARASITE ANTIGEN;

ARTICLE; CELL PROLIFERATION; CYTOKINE PRODUCTION; GENE EXPRESSION; GENE LIBRARY; GENE SEQUENCE; HOST PARASITE INTERACTION; IMMUNE RESPONSE; IMMUNOCYTOCHEMISTRY; IMMUNOGENICITY; LARVAL DEVELOPMENT; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, HELMINTH; BLOTTING, WESTERN; CLONING, MOLECULAR; CONSENSUS SEQUENCE; HORSES; HUMANS; IMMUNIZATION, PASSIVE; LEUKOCYTE ELASTASE; LIFE CYCLE STAGES; LYMPHOCYTE ACTIVATION; MICE; MOLECULAR SEQUENCE DATA; SCHISTOSOMA MANSONI; SWINE;

EID: 0033814685     PISSN: 00311820     EISSN: None     Source Type: Journal    
DOI: 10.1017/S003118209900640X     Document Type: Article

References (25)

1. The radiation-attenuated schistosome vaccine induces high levels of protective immunity in the absence of B cells
2. A purified 28,000 dalton protein from Schistosoma mansoni adult worms protects rats and mice against experimental schistosomiasis
3. Schistosomiasis vaccines: Research to development
4. Resistance against Schistosoma mansoni induced by highly irradiated infections: Studies on species specificity of immunization and attempts to transfer resistance
5. The protein antigens secreted in vivo by adult male Schistosoma mansoni
6. Cloning of a 21.7-kDa vaccine-dominant antigen gene of Schistosoma mansoni reveals an EF hand-like motif
7. Evaluation of cDNA libraries from different developmental stages of Schistosoma mansoni for production of expressed sequence tags (ESTs)
8. Characterization, cloning and immunogenicity of antigens released by lung-stage larvae of Schistosoma mansoni
9. Protein synthesis and release by cultured schistosomula of Schistosoma mansoni
10. Constructing and screening cDNA libraries in lambda gt10 and lambda gt11
11. Characterization of isolates of Schistosoma mansoni from Egyptian villagers that tolerate high doses of praziquantel
12. Cleavage of the structural proteins during the assembly of the head of bacteriophage T4
13. Purification and characterization of an elastinolytic proteinase secreted by cercariae of Schistosoma mansoni
14. Passive transfer with serum and IgG antibodies of irradiated cercaria-induced resistance against Schistosoma mansoni in mice
15. The role of IgG antibodies from irradiated cercaria-immunized rabbits in the passive transfer of immunity to Schistosoma mansoni-infected mice
16. Purification and characterization of proteases secreted by transforming schistosomula of Schistosoma mansoni
17. Vaccination against schistosomiasis: The case for lung-stage antigens
18. Antigens derived from lung-stage larvae of Schistosoma mansoni are efficient stimulators of proliferation and gamma interferon secretion by lymphocytes from mice vaccinated with attenuated larvae
19. Schistosoma mansoni: Characterization of sequence variants of the 28-kDa glutathione S-transferase
20. Rapid changes in the expression of a gene encoding a calcium binding protein in Schistosoma mansoni
21. Reactivity of anti-tegument monoclonal antibodies with target epitopes in different worm tissues and developmental stages of Schistosoma mansoni
22. Monoclonal antibody to interferon-gamma modifies pulmonary inflammatory responses and abrogates immunity to Schistosoma mansoni in mice vaccinated with attenuated cercariae
23. Efficacy and side effects of praziquantel in an endemic focus of Schistosoma mansoni
24. Migration of the schistosomula of Schistosoma mansoni in mice vaccinated with radiation-attenuated cercariae, and normal mice: An attempt to identify the timing and site of parasite death
25. Schistosoma mansoni : Fractionation and characterization of the glycocalyx and glycogen-like material from cercariae