Increased serum IgA and decreased IgG3 strongly correlate with increased serum TGF-β1 levels in patients with nonimmune chronic idiopathic neutropenia of adults

European Journal of Haematology

Volumn 65, Issue 4, 2000, Pages 237-244

  Papadaki, Helen A ^a   Palmblad, Jan ^b   Kapsimali, Violetta ^a   Anagnou, Nikolas P ^a   Eliopoulos, George D ^a,c  

^a UNIVERSITY OF CRETE   (Greece)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c UNIVERSITY HOSPITAL OF HERAKLION   (Greece)

Author keywords

IFN ; IgG subclasses; IL 4; Nonimmune chronic idiopathic neutropenia of adults; Serum immunoglobulins; Transforming growth factor 1 (TGF 1)

Indexed keywords

CYTOKINE; GAMMA INTERFERON; GRANULOCYTE ANTIBODY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G3; INTERLEUKIN 4; TRANSFORMING GROWTH FACTOR BETA1;

ADOLESCENT; ADULT; AGED; ANTIBODY DETECTION; ARTICLE; CHRONIC DISEASE; CONTROLLED STUDY; FEMALE; HUMAN; IDIOPATHIC DISEASE; IMMUNOGLOBULIN BLOOD LEVEL; INFLAMMATION; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NEUTROPENIA; PATHOGENESIS; PRIORITY JOURNAL; SERUM;

ADOLESCENT; ADULT; AGED; CHRONIC DISEASE; FEMALE; GAMMA-GLOBULINS; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INFLAMMATION; INTERFERON TYPE II; INTERLEUKIN-4; MALE; MIDDLE AGED; NEUTROPENIA; REGRESSION ANALYSIS; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0033814669     PISSN: 09024441     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0609.2000.065004237.x     Document Type: Article

References (32)

1. Chronic neutropenia
2. Natural history of chronic idiopathic neutropenia
3. Prevalence of chronic idiopathic neutropenia of adults among an apparently healthy population living on the island of Crete
4. Benign ethnic neutropenia: What is a normal absolute neutrophil count?
5. Enhanced neutrophil extravasation may be a contributing factor in the determination of neutropenia in patients with chronic idiopathic neutropenia of adults
6. Non-malignant neutropenia
7. Pathophysiology and treatment of severe chronic neutropenia
8. Two case studies of chronic idiopathic neutropenia preceding acute myeloid leukaemia
9. Leukokinetic studies. XIV. Blood neutrophil kinetics in chronic steady-state neutropenia
10. Idiopathic neutropenia with normocellular bone marrow: An immune complex disease
11. T-lymphocyte-mediated granulopoietic failure: In vitro identification of prednison-responsive patients
12. Increased in vitro neutrophil adherence in a case of chronic idiopathic neutropenia
13. Antibodies to myeloid precursor cells in autoimmune neutropenia
14. Neutrophil marrow in chronic benign idiopathic neutropenia
15. Defective CSA-dependent granulopoiesis in patients with chronic neutropenia
16. The chronic idiopathic neutropenia syndrome: Correlation of clinical features with in vitro parameters of granulopoiesis
17. Chronic idiopathic neutropenia. Granulopoietic assessment by bone marrow culture and granulocyte kinetics
18. 1 by bone marrow stromal cells
19. Chronic idiopathic neutropenia associated with abnormal expression of granulocyte colony-stimulating factor mRNA of bone marrow stromal cells
20. Impaired G-CSF production at post-transcriptional level in a patient with chronic idiopathic neutropenia
21. + T-lymphocytes correlates with increased levels of serum cytokines and endothelial cell-derived cell adhesion molecules in patients with chronic idiopathic neutropenia of adults
22. Low numbers of peripheral blood natural killer cells in patients with chronic idiopathic neutropenia of adults is probably due to enhanced extravasation into the tissues
23. Patients with chronic idiopathic neutropenia of adults have increased serum concentrations of inflammatory cytokines and chemokines
24. Chronic autoimmune neutropenia due to anti-NA2 antibody
25. Morphologically defined myeloid cell compartments, lymphocyte subpopulations and histological findings of bone marrow in patients with nonimmune chronic idiopathic neutropenia of adults
26. A two-signal model for regulation of immunoglobulin isotype switchng
27. Differential effects of transforming growth factor-beta 1 on IgA vs IgG(2b) production by lipopolysaccharide-stimulated lymph node B cells: A comparative study with spleen B cells
28. Molecular analysis of IgA deficiency. Evidence for impaired switching to IgA
29. Modulation of the immune response by transforming growth factor beta
30. Transforming growth factor-beta inhibits the production of IgG, IgM, and IgA in human lymphocyte cultures
31. - B cells