A rapid, sensitive assay for cocaine and its metabolites in biological fluids using solid-phase extraction and high-performance liquid chromatography

Journal of Analytical Toxicology

Volumn 24, Issue 6, 2000, Pages 438-441

  Jamdar, Subhash C ^a   Pantuck, Carol B ^a   Diaz, Jaime ^a   Mets, Berend ^a  

^a NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOYLECGONINE; COCAINE; ECGONINE METHYL ESTER; NORCOCAINE;

ARTICLE; BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; QUANTITATIVE ASSAY; RAT; SOLID PHASE EXTRACTION; SUBSTANCE ABUSE; URINE LEVEL;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COCAINE; MALE; RATS; RATS, SPRAGUE-DAWLEY; SENSITIVITY AND SPECIFICITY; SUBSTANCE ABUSE DETECTION;

EID: 0033812926     PISSN: 01464760     EISSN: None     Source Type: Journal    
DOI: 10.1093/jat/24.6.438     Document Type: Article

References (13)

1. The cardiovascular effects of cocaine
2. Cocaine and the liver
3. Recurrent Coronary vasoconstriction caused by intranasal cocaine: Possible role for metabolites
4. Simultaneous measurement of cocaine, cocaethylene, their metabolites, and 'crack' pyrolysis products by gas chromatography-mass spectrometry
5. Identification and quantitation of cocaine and its metabolites, benzoylecgonine and ecgonine methyl ester, in hair of bolivian coca chewers by gas chromatography/mass spectrometry
6. Hair analysis for drugs of abuse: VII. The incorporation rates of cocaine, benzoylecgonine and ecgonine methyl ester into rat hair and hydrolysis of cocaine in rat hair
7. The analysis of cocaine and its metabolites by liquid chromatography/atmospheric pressure chemical ionization-mass spectrometry (LC/APCI-MS)
8. Analysis of cocaine, benzoylecgonine, ecgonine methyl ester, ethylcocaine and norcocaine in human urine using HPLC with post-column ion-pair extraction and fluorescence detection
9. Determination of cocaine, benzoylecgonine and ecgonine methyl ester in plasma by reversed-phase high-performance liquid chromatography
10. Determination of cocaine, norcocaine, benzoylecgonine and ecgonine methyl ester in rat plasma by high-performance liquid chromatography with ultraviolet detection
11. Sensitive and specific high-performance liquid chromatographic assay with ultraviolet detection for the determination of cocaine and its metabolites in rat plasma
12. Cocaine, norcocaine, ecgonine methylester and benzoylecgonine pharmacokinetics in the rat
13. A method for the simultaneous determination of cocaine, benzoylecgonine, and ecgonine methyl ester in blood and urine using GC/EIMS with derivatization to produce high mass molecular ions