Propofol and thiopental attenuate the contractile response to vasoconstrictors in human and porcine coronary artery segments

European Journal of Anaesthesiology

Volumn 17, Issue 8, 2000, Pages 485-490

  Klockgether Radke, A P ^a   Frerichs, A ^a   Kettler, D ^a   Hellige, G ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Anaesthetics, intravenous, propofol, thiopental; Arteries, coronary vessels; Endothelium

Indexed keywords

ACETYLCHOLINE; ENDOTHELIAL CELL GROWTH FACTOR; HISTAMINE; INTRAVENOUS ANESTHETIC AGENT; PROPOFOL; SEROTONIN; THIOPENTAL; VASOCONSTRICTOR AGENT;

ANESTHESIA MECHANISM; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DILATATION; DOSE RESPONSE; DRUG EFFECT; HUMAN; HUMAN TISSUE; INTRAVENOUS ANESTHESIA; NONHUMAN;

ACETYLCHOLINE; ANESTHETICS, INTRAVENOUS; ANIMALS; CORONARY VESSELS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; HISTAMINE; HUMANS; MUSCLE, SMOOTH, VASCULAR; PROPOFOL; SEROTONIN; SWINE; THIOPENTAL; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASODILATION; VASODILATOR AGENTS;

EID: 0033811801     PISSN: 02650215     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2346.2000.00713.x     Document Type: Article

References (44)

1. Association of perioperative myocardial ischemia with cardiac morbidity and mortality in men undergoing noncardiac surgery
2. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
3. Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels
4. 2, and prostacyclin
5. Clinical implications of endothelial dysfunction
6. Cardiovascular effects of propofol in the anaesthetized dog
7. Direct vasoconstrictor and vasodilator effects of propofol in isolated dog arteries
8. Mechanisms whereby propofol mediates peripheral vasodilation in humans. Sympatho-inhibition or direct vascular relaxation?
9. Action of propofol on central sympathetic mechanisms controlling blood pressure
10. Propofol stimulates nitric oxide release from cultured porcine endothelial cells
11. The effect of endothelium on the response to propofol on bovine coronary artery rings
12. Propofol-associated dilation of rat distal coronary arteries is mediated by multiple substances, including endothelium-derived nitric oxide
13. 2+ channel blocker
14. Propofol induces dilation and inhibits constriction in guinea pigs basilar arteries
15. Vasodilation and mechanism of action of propofol in porcine coronary artery
16. Do muscle relaxants influence vascular tone in isolated coronary artery segments?
17. ICI 35868, a new intravenous induction agent
18. Effects of thioentone, etomidate and propofol on systemic vascular resistance during cardiopulmonary bypass
19. Effects of propofol on cardiovascular dynamics, myocardial blood flow and myocardial metabolism in patients with coronary artery disease
20. Anesthesia and myocardial ischemia: The gains of the past have largely come from control of myocardial oxygen demand; the breakthroughs of the future will involve optimizing myocardial oxygen supply
21. Pharmacokinetics of propofol (diprivan) in elderly patients
22. Plasma levels of thiopental necessary for anesthesia
23. The role of metabolism and protein binding in thiopental anesthesia
24. Propofol differentially attenuates the responses to exogenous and endogenous norepinephrine in the isolated rat femoral artery in vitro
25. The contractile response of isolated dog cerebral and extracerebral arteries to oxybarbiturates and thiobarbiturates
26. Effects of propofol on isolated rabbit mesenteric arteries and veins
27. Responses to barbiturates of isolated dog cerebral and mesenteric arteries contracted with KCI and prostaglandin F2α
28. Effects of propofol and thiopental in isolated rat aorta and pulmonary artery
29. Effects of thiopental, pentobarbital, and ketamine on endothelin-induced constriction of porcine cerebral arteries
30. Barbiturates inhibit endothelium-dependent and independent relaxations mediated by cyclic GMP
31. Comparison of the vasodilator effects of thiopentone and pentobarbitone
32. Thiobarbiturates suppress depolarization-induced contraction of vascular smooth muscle without suppression of calcium influx
33. Effects of thiopental on endothelium-dependent responses in rat aorta
34. Vasorelaxant effect of thiopentone in isolated human epigastric arteries
35. Thiopental attenuates relaxation and cyclic GMP production in vascular smooth muscle of endotoxin-treated rat aorta, independent of nitric oxide production
36. + channels
37. Role of the endothelium in the relaxation induced by propofol and thiopental in isolated arteries from man
38. Inhibitory effects of propofol on intracellular signaling by endothelin-1 in aortic smooth muscle cells
39. 2+](i) and force in smooth muscle of the rabbit mesenteric resistance artery
40. Propofol-induced relaxation of rat mesenteric arteries: Evidence for a cyclic GMP-mediated mechanism
41. 2 synthesis
42. Thiopental and propofol impair relaxation produced by ATP-sensitive potassium channel openers in the rat aorta
43. Relaxant effects of propofol on human omental arteries and veins
44. Differential relaxant effect of high concentrations of intravenous anesthetics on endothelin-constricted proximal and distal canine coronary arteries